FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term)

Details for Product anti-FOXC2 Antibody No. ABIN249942, Supplier: Log in to see
Antigen
  • FOXC2
  • Fkh14
  • Hfhbf3
  • MFH-1
  • Mfh1
  • Fkhl14
  • FKHL14
  • LD
  • MFH1
  • forkhead box C2 (MFH-1, mesenchyme forkhead 1)
  • forkhead box C2
  • FOXC2
  • Foxc2
Epitope
C-Term
23
22
18
10
9
9
9
9
9
8
7
7
7
5
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
125
14
12
11
10
9
3
3
3
Host
Goat
54
54
17
1
Clonality
Polyclonal
Conjugate
This FOXC2 antibody is un-conjugated
7
7
7
6
6
6
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
117
96
35
32
8
8
7
1
1
1
1
Options
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Immunogen Peptide with sequence RHAAPYSYDCTKY corresponding to C-Terminus according to NP_005242.1.
Purification Immunogen affinity purified
Alternative Name FoxC2 (FOXC2 Antibody Abstract)
Background Gene Symbol: FOXC2
Molecular Weight Theoretical MW: 54 kDa
Gene ID 2303
UniProt Q99958
Application Notes Western Blot 1-3 μg/mL, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10 - 1:500, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1:10-1:500, Peptide ELISA detection limit 1:8000WB: In transfected HEK293 transiently expressing full-length human FOXC2 (myc and DYKDDDDK tagged), a band of approx. 65 kDa band was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag antibody. IHC-P: Human breast cancer shows nuclear staning with some weak cytoplasm staining. ICC/IF and IHC-F usage are reported in scientific literature (PMID: 23862012). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 0.5 mg/mL Tris ( pH 7.3) and 0.5 % BSA
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term) (ABIN249942) Western Blot: FOX C2 Antibody [ABIN249942] - ABIN249942 staining (1ug/ml) of Human Br...
Western Blotting (WB) image for anti-FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term) (ABIN249942) Western Blot: FoxC2 Antibody [ABIN249942] - HEK293 lysate (10ug protein in RIPA buffe...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term) (ABIN249942) Immunohistochemistry-Paraffin: FoxC2 Antibody [ABIN249942] - FOXC2 Antibody [ABIN2499...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term) (ABIN249942) Immunohistochemistry-Paraffin: FoxC2 Antibody [ABIN249942] - staining of paraffin emb...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FOXC2 antibody (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1)) (C-Term) (ABIN249942) Immunohistochemistry-Paraffin: FoxC2 Antibody [ABIN249942] - staining of paraffin emb...
Product cited in: Siegenthaler, Choe, Patterson, Hsieh, Li, Jaminet, Daneman, Kume, Huang, Pleasure: "Foxc1 is required by pericytes during fetal brain angiogenesis." in: Biology open, Vol. 2, Issue 7, pp. 647-59, 2013 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen Sections)

Zarbalis, Siegenthaler, Choe, May, Peterson, Pleasure: "Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 35, pp. 14002-7, 2007 (PubMed).

Dagenais, Hartsough, Erickson, Witte, Butler, Glover: "Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome." in: Gene expression patterns : GEP, Vol. 4, Issue 6, pp. 611-9, 2004 (PubMed).

Brice, Mansour, Bell, Collin, Child, Brady, Sarfarazi, Burnand, Jeffery, Mortimer, Murday: "Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24." in: Journal of medical genetics, Vol. 39, Issue 7, pp. 478-83, 2002 (PubMed).