CLOCK antibody (Clock Homolog (Mouse))

Details for Product anti-CLOCK Antibody No. ABIN249944, Supplier: Log in to see
Antigen
  • CG7391
  • CLK
  • CLOCK
  • Dmel\\CG7391
  • Jerk
  • Jrk
  • PAS1
  • bHLHe10
  • clk
  • clock
  • dCLK
  • dCLK/JRK
  • dCLOCK
  • dClck
  • dClk
  • dClock
  • dclk
  • jrk
  • Xclk
  • XClock
  • zCLOCK1
  • zfCLOCK1
  • 5330400M04Rik
  • KAT13D
  • bHLHe8
  • mKIAA0334
  • Clock
  • clock homolog (mouse)
  • clock circadian regulator
  • clock homolog
  • clock
  • circadian locomotor output cycles kaput
  • Clk
  • CLOCK
  • clock
  • Clock
Alternatives
anti-Mouse (Murine) CLOCK antibody for Chromatin Immunoprecipitation
Reactivity
Human, Mouse (Murine)
106
53
37
5
5
4
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
67
37
12
1
Clonality
Polyclonal
Conjugate
This CLOCK antibody is un-conjugated
2
2
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
107
44
27
18
10
9
9
4
4
3
2
1
Options
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Immunogen Two peptides derived from mouse CLOCK conjugated to albumin. [UniProt# O08785]
Purification Unpurified
Alternative Name CLOCK (CLOCK Antibody Abstract)
Background Gene Symbol: CLOCK
Gene ID 9575
UniProt O08785
Research Area Cardiovascular, Atherosclerosis, Transcription Factors, Metabolism
Pathways Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
Application Notes Western Blot 1:1000, Chromatin Immunoprecipitation 1:10-1:500This CLOCK antibody is useful for Western blot and Chromatin Immunoprecipitation. It has been tested against bacterially expressed fragment of CLOCK expressed in BL21 cells or the full length protein expressed in an in vitro translation system (reticulocyte lysate).
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer Whole antisera
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-CLOCK antibody (Clock Homolog (Mouse)) (ABIN249944) Lanes 3-5 contained alpha CLOCK immunoprecipitated DNA (15, 10 and 5 ul of antisera a...
Product cited in: Menet, Rodriguez, Abruzzi, Rosbash: "Nascent-Seq reveals novel features of mouse circadian transcriptional regulation." in: eLife, Vol. 1, pp. e00011, 2012 (PubMed). (Sample species: Mouse (Murine)). Further details: Chromatin Immunoprecipitation

Xu, Krager, Liao, Tischkau: "Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 1, pp. 98-108, 2010 (PubMed). (Sample species: Mouse (Murine)). Further details: Chromatin Immunoprecipitation

Muñoz, Brewer, Baler: "Circadian Transcription. Thinking outside the E-Box." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36009-17, 2002 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Background publications Jin, Shearman, Weaver, Zylka, de Vries, Reppert: "A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock." in: Cell, Vol. 96, Issue 1, pp. 57-68, 1999 (PubMed).

Shearman, Weaver: "Photic induction of Period gene expression is reduced in Clock mutant mice." in: Neuroreport, Vol. 10, Issue 3, pp. 613-8, 1999 (PubMed).

Hogenesch, Gu, Jain, Bradfield: "The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 10, pp. 5474-9, 1998 (PubMed).