Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) antibody

Details for Product No. ABIN250128
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Antigen
Synonyms ASD8, MRG-1, MRG1, P35SRJ, VSD2, Mrg1, Msg2, p35srj, AI835299, ER154-like, mrg1, zgc:103418, CITED2, cite2
Reactivity
Human
(24), (14), (10), (3), (2), (1), (1), (1)
Host
Mouse
(16), (6), (5), (1)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
(24), (12), (7), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN250128
Quantity 25 µL
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Immunogen Human CITED 2 protein.
Clone JA22
Isotype IgG1
Specificity This antibody is specific for CITED 2. Species Reactivity: Human. Does not work well on mouse. Other species have not been tested. Localization: Nuclear.
Cross-Reactivity Human
Purification Ascites
Alternative Name CITED2
Background Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interactingtranscriptional modulator and a proposed negative regulator for hypoxia-induciblefactor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptionalresponse to hypoxia. Alternate Names: anti-CITED2 antibody, anti-Cbp/p300-interacting transactivator antibody, anti-withGlu/Asp-rich carboxy-terminal domain antibody, anti-2 antibody, anti-HGNC:1987antibody, anti-MRG1 antibody, anti-P35SRJ antibody, anti-CITED 2 antibody.
Gene ID 10370
Research Area Cancer
Application Notes Suggested working dilutions: Western Blot 1:500
Restrictions For Research Use only
Format Liquid
Concentration 22.4 mg/ml
Storage -20 °C
General Bhattacharya, Michels, Leung et al.: "Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1." in: Genes & development, Vol. 13, Issue 1, pp. 64-75, 1999 (PubMed).

Tien, Davis, Vanden Heuvel: "Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24053-63, 2004 (PubMed).

Haase, Schott, Bornstein et al.: "CITED2 is expressed in human adrenocortical cells and regulated by basic fibroblast growth factor." in: The Journal of endocrinology, Vol. 192, Issue 2, pp. 459-65, 2007 (PubMed).

Hosts (16), (6), (5), (1)
Reactivities (24), (14), (10), (3), (2), (1), (1), (1)
Applications (24), (12), (7), (1), (1), (1)
Epitopes (8), (6), (3), (2), (2), (1), (1)
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