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Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) antibody

Antigen

Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2)
Synonyms MRG1, P35SRJ, Mrg1, Msg2, p35srj, AI835299, ER154-like, MGC93288, CITED2, mrg1, MGC75612, cited2, MGC140571, cite2
Clonality Monoclonal (JA22)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Western Blotting (WB)
3 references available
Catalog no. ABIN250128
Quantity 25 µl  (22.4 mg/ml)  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name CITED2
Gene ID 10370
Immunogen Human CITED 2 protein.
Cross-Reactivity Human
Format Ascites
Isotype IgG1
Clone JA22
Description Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interactingtranscriptional modulator and a proposed negative regulator for hypoxia-induciblefactor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptionalresponse to hypoxia. Alternate Names: anti-CITED2 antibody, anti-Cbp/p300-interacting transactivator antibody, anti-withGlu/Asp-rich carboxy-terminal domain antibody, anti-2 antibody, anti-HGNC:1987antibody, anti-MRG1 antibody, anti-P35SRJ antibody, anti-CITED 2 antibody.
Specificity This antibody is specific for CITED 2. Species Reactivity: Human. Does not work well on mouse. Other species have not been tested. Localization: Nuclear.

Application Details
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Application Notes Suggested working dilutions: Western Blot 1:500
Concentration 22.4 mg/ml
Purification Ascites
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Research Area Cancer
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Bhattacharya, Michels, Leung et al.: "Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1." in: Genes & development, Vol. 13, Issue 1, pp. 64-75, 1999 (PubMed).

Tien, Davis, Vanden Heuvel: "Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24053-63, 2004 (PubMed).

Haase, Schott, Bornstein et al.: "CITED2 is expressed in human adrenocortical cells and regulated by basic fibroblast growth factor." in: The Journal of endocrinology, Vol. 192, Issue 2, pp. 459-65, 2007 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2)", type "Antibodies"
Hosts Rabbit (15), Goat (3), Mouse (2)
Reactivities Human (18), Mouse (Murine) (10), Rat (Rattus) (9), Cow (Bovine) (3), Chicken (2), Cat (Feline) (1), Dog (Canine) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (17), ELISA (14), Immunofluorescence (IF) (4), Immunocytochemistry (ICC) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Epitopes C-Term (4), N-Term (4), Internal Region (3)