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Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) (C-Term) antibody

Details for Product No. ABIN250155
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Antigen
Synonyms VPS26A, DKFZp459G2011, HB58, Hbeta58, PEP8A, VPS26, Vps26, AA407240, MNC6.7, MNC6_7, vacuolar protein sorting 26A
Epitope
C-Term
(10), (5), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(30), (6), (6), (1), (1)
Host
Goat
(22), (6), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(29), (15), (7), (3), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN250155
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Immunogen Synthetic peptide SPESQASAEQPEM, representing the C-Terminus of the human protein according to NP_004887
Isotype IgG
Specificity This antibody is expected to recognize isoform 1 (NP_004887.2) only.
Cross-Reactivity (Details) Expected cross reactivity from sequence similarity: Mouse, Rat, Pig,Cow.
Purification affinity purified
Alternative Name VPS26A
Background This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encodedprotein is a component of a large multimeric complex, termed the retromer complex,involved in retrograde transport of proteins from endosomes to the trans-Golgi network.The close structural similarity between the yeast and human proteins that make up thiscomplex suggests a similarity in function. Expression studies in yeast and mammaliancells indicate that this protein interacts directly with VPS35, which serves as the core ofthe retromer complex. Alternate Names: anti-VPS26A antibody, anti-FLJ12930 antibody, anti-HB58 antibody, anti-Hbeta58antibody, anti-Hbeta58 homolog antibody, anti-hVPS 26 antibody, anti-hVPS26antibody, anti-PEP 8A antibody, anti-PEP8A antibody, anti-Vacuolar protein sorting 26 Aantibody, anti-Vacuolar protein sorting 26 antibody, anti-Vacuolar protein sorting 26homolog A antibody, anti-Vacuolar protein sorting 26 yeast antibody, anti-Vacuolarprotein sorting 26A antibody, anti-Vacuolar protein sorting associated protein 26Aantibody, anti-Vesicle protein sorting 26 antibody, anti-Vesicle protein sorting 26Aantibody, anti-VPS 26 antibody, anti-VPS 26A antibody, anti-VPS26A antibody.
Gene Symbol: VPS26A
Gene ID 9559
NCBI Accession NP_004887
Application Notes Approx 40kDa band observed in Human Kidney lysates (predicted size of approx. 38kDa according to NP_004887.2).
Recommended dilutions: Peptide ELISA detection limit 1:4000, Western Blot 1-3 µg/mL
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline containing [pH 7.3] with 0.5 % BSA, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.
Supplier Images
anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) (C-Term) antibody ABIN250155 staining (1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
General He, Li, Chang et al.: "GGA proteins mediate the recycling pathway of memapsin 2 (BACE)." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 11696-703, 2005 (PubMed).

Validation Images
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