CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2) antibody

Details for Product No. ABIN250400
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Synonyms FWP010, LIN1, PPP1R59, Snu40, U5-52K, 1500011B02Rik, 2410024K20Rik, AW048183
(9), (1), (1)
(5), (4)
ELISA, Western Blotting (WB)
(7), (3), (3), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN250400
Quantity 0.1 mg
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Immunogen Synthetic peptide with sequence PKRKVTFQGVGDE-C, representing the N Terminus ofthe human protein according to NP_006101.1. Reference Sequence: NP_006101.1.
Isotype IgG
Specificity This antibody is specific for CD2BP2. Species Reactivity: Cross reacts with Human, Mouse and Rat.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Affinity Purified
Alternative Name CD2BP2
Background CD2BP2 is an intracellular protein which binds to a site containing two PPPGHRsegments within the cytoplasmic region of CD2. Mutagenesis and NMR analysisdemonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motifalso found in several yeast and Caenorhabditis elegans proteins of unknown function. InJurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2enhances the production of interleukin 2 on crosslinking of CD2 but not the T cellreceptor. Alternate Names: anti-CD2 (cytoplasmic tail) binding protein 2 antibody, anti-CD2 antigen (cytoplasmictail) binding protein 2 antibody, anti-FWP010 antibody, anti-LIN1 antibody, anti-Snu40antibody.
Gene ID 10421, 70233
NCBI Accession NP_0061011
Research Area Immunology, Adaptive Immunity, CD Antigens
Application Notes Suggested working dilutions: ELISA 1:32,000,Western Blot 0.3-1.0ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline containing 0.02% sodium azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2) antibody Western Blot: CD2BP2 Antibody [ABIN250398] - ABIN250400 (0.3ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General Nishizawa, Freund, Li et al.: "Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 25, pp. 14897-902, 1999 (PubMed).

Hosts (5), (4)
Reactivities (9), (1), (1)
Applications (7), (3), (3), (3), (2), (1)
Epitopes (6), (3), (1), (1), (1)
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