Reticulon 4 Receptor (RTN4R) antibody

Details for Product No. ABIN250419
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Antigen
Synonyms NGR, NOGOR, NgR, NgR1, Nogor
Reactivity
Human
(12), (4), (3), (2)
Host
Goat
(8), (4), (2), (1)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(11), (4), (4), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN250419
Quantity 0.1 mg
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Immunogen Synthetic peptide with sequence C-LQALPDDTFRDLGN, representing the internalregion of the human protein according to NP_075380.1. Reference Sequence: NP_075380.1.
Isotype IgG
Specificity This antibody is specific for Nogo 66 receptor. Species Reactivity: Human, Mouse, Rat, Dog.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Affinity Purified
Alternative Name Nogo 66 receptor
Background This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein andmyelin-associated glycoprotein. This receptor mediates axonal growth inhibition andmay play a role in regulating axonal regeneration and plasticity in the adult centralnervous system. Alternate Names: anti-RTN4R antibody, anti-reticulon 4 receptor antibody, anti-HGNC antibody, anti-1860antibody, anti-NGR antibody, anti-NOGOR antibody, anti-Nogo-66 receptor antibody,anti-UNQ330/PRO526 antibody, anti-nogo receptor antibody, anti-reticulon 4 receptorprecursor antibody.
Gene ID 65078
NCBI Accession NP_0753801
Application Notes Suggested working dilutions: ELISA 1:16,000,Western Blot 0.3 to 1 ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline, pH7.3 with 0.5% BSA. Preservative: 0.02% Sodium azide.
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-Reticulon 4 Receptor (RTN4R) antibody Western Blot: Nogo 66 receptor Antibody [ABIN250419] - ABIN250419 (0.3ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
General Shao, Browning, Lee et al.: "TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration." in: Neuron, Vol. 45, Issue 3, pp. 353-9, 2005 (PubMed).

Hosts (8), (4), (2), (1)
Reactivities (12), (4), (3), (2)
Applications (11), (4), (4), (2), (2)
Epitopes (4), (2), (1)
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