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NGFR antibody (Nerve Growth Factor Receptor) (Internal Region)

Details for Product anti-NGFR Antibody No. ABIN250425, Supplier: Log in to see
Antigen
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
Alternatives
anti-Human NGFR antibody for Flow Cytometry
Epitope
Internal Region
23
20
15
13
9
7
7
5
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
245
93
82
19
17
15
14
12
9
8
6
5
2
1
1
1
1
1
Host
Goat
130
109
32
4
1
Clonality
Polyclonal
Conjugate
This NGFR antibody is un-conjugated
15
15
13
12
5
4
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
187
106
79
78
62
41
34
30
14
13
11
7
6
5
4
2
1
1
Supplier
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Immunogen Synthetic peptide with sequence C-AKREEVEKLLNG, representing the internal region of the human protein according to NP_002498.
Isotype IgG
Cross-Reactivity (Details) Expected cross reactivity from sequence similarity: Mouse, Rat, Dog,Cow.
Purification affinity purified
Alternative Name CD271 / NGFR (NGFR Antibody Abstract)
Background Nerve growth factor receptor contains an extracellular domain containing four 40-aminoacid repeats with 6 cysteine residues at conserved positions followed by aserine/threonine-rich region, a single transmembrane domain, and a 155-amino acidcytoplasmic domain. The cysteine-rich region contains the nerve growth factor bindingdomain. Alternate Names: anti-NGFR antibody, anti-nerve growth factor receptor (TNFR superfamily antibody,anti-member 16) antibody, anti-HGNC antibody, anti-7809 antibody, anti-TNFRSF16antibody, anti-p75(NTR) antibody, anti-p75NTR antibody.
Gene Symbol: NGFR
Gene ID 4804
NCBI Accession NP_002498
Research Area Growth Factors, Receptors
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway
Application Notes Approx 75kDa band observed in Human Duodenum and Human Heart lysates (calculated MW of 45.2kDa according to NP_4804), recommended concentration: 0.3-1ug/ml..
Recommended dilutions: Peptide ELISA <1:32000, Western Blot 1:1000
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline [pH 7.3] containing 0.5 % BSA, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.
Supplier Images
Western Blotting (WB) image for anti-NGFR antibody (Nerve Growth Factor Receptor) (Internal Region) (ABIN250425) Western Blot: NGFR Antibody [ABIN250425] - ABIN250425 (0.3ug/ml) staining of Human He...
Product cited in: Nykjaer, Willnow, Petersen: "p75NTR--live or let die." in: Current opinion in neurobiology, Vol. 15, Issue 1, pp. 49-57, 2005 (PubMed).