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Details for Product No. ABIN250425

Nerve Growth Factor Receptor (NGFR) antibody

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Antigen
Synonyms CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, ngfr, wu:fb38c02, wu:fc10h01, NRH1b, fullback, nrh1, p75ntr, tnfrsf16
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN250425
Quantity 0.1 mg
Price
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Immunogen Synthetic peptide with sequence C-AKREEVEKLLNG, representing the internal regionof the human protein according to NP_002498.1. Reference Sequence: NP_002498.1.
Isotype IgG
Specificity This antibody is specific for NGFR. Species Reactivity: Human, Mouse, Rat, Dog.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Affinity Purified
Alternative Name CD271 / NGFR
Background Nerve growth factor receptor contains an extracellular domain containing four 40-aminoacid repeats with 6 cysteine residues at conserved positions followed by aserine/threonine-rich region, a single transmembrane domain, and a 155-amino acidcytoplasmic domain. The cysteine-rich region contains the nerve growth factor bindingdomain. Alternate Names: anti-NGFR antibody, anti-nerve growth factor receptor (TNFR superfamily antibody,anti-member 16) antibody, anti-HGNC antibody, anti-7809 antibody, anti-TNFRSF16antibody, anti-p75(NTR) antibody, anti-p75NTR antibody.
Gene ID 4804
NCBI Accession NP_0024981
Research Area Growth Factors, Receptors
Application Notes This antibody can be used in ELISA and Western Blot where a 75kDa band has beenobserved in Human Duodenum and Human Heart lysates. Predicted MW is 45.2kDaaccording to NP_4804. The observed molecular weight corresponds to earlier findingsin literature (Nykjaer et al, Curr Opin Neurobiol. 2005 Feb,15(1):49-57). Recommendeddilutions: ELISA 1/32,000. WB: 0.3-1.0ug/ml. *Optimal dilutions should be determined bythe end user.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline containing 0.02% sodium azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Storage -20 °C
Nykjaer, Willnow, Petersen: "p75NTR--live or let die." in: Current opinion in neurobiology, Vol. 15, Issue 1, pp. 49-57, 2005 (PubMed).

Alternatives for antigen "Nerve Growth Factor Receptor (NGFR)", type "Antibodies"
Hosts (89), (67), (11), (4), (1)
Reactivities (134), (68), (65), (37), (14), (14), (13), (11), (5), (5), (4), (3)
Applications (109), (62), (56), (53), (40), (34), (30), (26), (20), (20), (5), (4), (3), (1), (1), (1), (1)
Conjugates (8), (7), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (7), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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