Parvalbumin (PVALB) (C-Term) antibody

Details for Product No. ABIN250430
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Antigen
Synonyms pvalb1, pvalb, zgc:92782, MGC107903, zgc:56217, zgc:77798, D22S749, PALB1, Pva, PV, Parv, ATH, PVALB, thymic
Epitope
C-Term
(9), (2), (1), (1)
Reactivity
Human, Rat (Rattus)
(38), (31), (26), (12), (12), (12), (2)
Host
Goat
(31), (7), (7), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(29), (15), (12), (11), (10), (7), (4), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN250430
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Immunogen Synthetic peptide with sequence C-GVDEFSTLVAES, representing the C Terminus of the human protein according to NP_002845.
Isotype IgG
Purification affinity purified
Alternative Name Parvalbumin alpha / PVALB
Background The protein encoded by this gene is a high affinity calcium ion-binding protein that isstructurally and functionally similar to calmodulin and troponin C. The encoded protein isthought to be involved in muscle relaxation. Alternate Names: anti-PVALB antibody, anti-parvalbumin antibody, anti-HGNC antibody, anti-9704antibody, anti-D22S749 antibody, anti-parvalbumin alpha antibody.
Gene Symbol: PVALB
Gene ID 5816, 25269
NCBI Accession NP_002845
Application Notes Approx 12kDa band observed in Human Brain lysates (calculated MW of 12.1kDa according to NP_002845.1). Approx 10-12kDa band observed in rat skeletal muscle and in rat heart cells transfected with human PVALB, but not in untransfected rat heart cells.
Recommended dilutions: Peptide ELISA detection limit 1:32000, Western Blot 0.1-0.3 µg/mL
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline [pH 7.3] containing 0.5 % BSA, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.
Supplier Images
anti-Parvalbumin (PVALB) (C-Term) antibody anti-Parvalbumin (PVALB) (C-Term) antibody
anti-Parvalbumin (PVALB) (C-Term) antibody (2) ABIN250430 (0.15?g/ml) staining of adenovirus-mediated gene transfer in rat heart cells 1) Untransfected, 2) transient transfection with Human PVALB. 3) Untransfected rat skeletal muscle. Primary incubation was 1 hour. Detected by chemiluminescence.
General Hashimoto, Bergen, Nguyen et al.: "Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 2, pp. 372-83, 2005 (PubMed).

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