Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody

Details for Product No. ABIN250437
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Antigen
Synonyms ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM, Cyp19, Cyp19a, p450arom, Aromatase, P450AROM, Ar, ArKO, Int-5, Int5, CYP19P1, CYP19A1, P450 arom, aro, cyp19, cyp19a, p450arom-A
Reactivity
Cow (Bovine), Horse (Equine), Human, Monkey, Rabbit
(92), (59), (41), (40), (39), (37), (13), (8), (7), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(74), (23), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(72), (42), (31), (30), (19), (12), (10), (4), (3), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN250437
Quantity 25 µL
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Immunogen A synthetic peptide made to a C-terminal portion of the human aromatase proteinsequence (between residues 400-502).
Specificity This antibody is specific for aromatase. Species Reactivity: Reacts with human, bovine, rabbit and primate. 83% sequence identity with pig, 81%sequence identity with Sheep, Goat, and Canine proteins. Localization: Membrane-bound.
Cross-Reactivity Human
Alternative Name Aromatase
Background Aromatase is a key enzyme in steroidogenesis and plays an important role in sexualdifferentiation, fertility, and carcinogenesis. Many environmental chemicals mayinfluence aromatase activity and thereby disrupt endocrine function. Alternate Names: anti-ARO1 antibody, anti-CYAR antibody, anti-CYP19 antibody, anti-CYP19A1 antibody,anti-CYPXIX antibody, anti-Cytochrome P450 19A1 antibody, anti-Estrogen synthetaseantibody, anti-P-450AROM antibody.
Gene ID 1588
Research Area Cancer, Endocrine system, Enzymes
Application Notes Suggested working dilutions: Western Blot 1 ug/ml
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml
Buffer Tris-citrate / phosphate [pH 7-8]. Preservative: 0.1% sodium azide.
Preservative Sodium azide
Storage 4 °C
Supplier Images
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibody
General Beyer, Green, Barker et al.: "Aromatase-immunoreactivity is localised specifically in neurones in the developing mouse hypothalamus and cortex." in: Brain research, Vol. 638, Issue 1-2, pp. 203-10, 1994 (PubMed).

Bogan, Murphy, Stouffer et al.: "Systematic determination of differential gene expression in the primate corpus luteum during the luteal phase of the menstrual cycle." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 5, pp. 1260-73, 2008 (PubMed).

Bogan, Murphy, Hennebold: "Dynamic changes in gene expression that occur during the period of spontaneous functional regression in the rhesus macaque corpus luteum." in: Endocrinology, Vol. 150, Issue 3, pp. 1521-9, 2009 (PubMed).

Hosts (74), (23), (7)
Reactivities (92), (59), (41), (40), (39), (37), (13), (8), (7), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Applications (72), (42), (31), (30), (19), (12), (10), (4), (3), (1), (1), (1)
Conjugates (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1)
Epitopes (18), (8), (6), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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