RAD51 Homolog D (S. Cerevisiae) (RAD51D) antibody

Details for Product No. ABIN250467
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Antigen
Synonyms BROVCA4, R51H3, RAD51L3, TRAD, ATRAD51D, F24B9.14, F24B9_14, SSN1, SUPPRESOR OF SNI1, homolog of RAD51 D, CG6318, Dm CG6318, Dmel\\CG6318, RAD51D, Rad51d, hmm140104
Reactivity
Human
(44), (3), (3), (1)
Host
Rabbit
(28), (13), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(41), (17), (7), (5), (3), (2), (1), (1)
Pubmed 5 references available
Catalog no. ABIN250467
Quantity 25 µL
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Immunogen A peptide from human RAD51D (homologue 4).
Specificity This antibody is specific for hRAD51D. There is no cross-reactivity observed withXRCC2, XRCC3, RAD51, RAD51B, or RAD51C. Species Reactivity: ABIN151188 reacts with human RAD51D. It does not work in mouse. Other specieshave not been tested.
Cross-Reactivity Human
Purification Aff - Purified
Alternative Name RAD51L3
Background Five human RAD51 homologues have been identified: XRCC2, XRCC3, RAD51B,RAD51C, and RAD51D. Each of these homologues interacts with one or more of theother four, with all of the proteins involved in one complex or multiple smallercomplexes. RAD51D interacts with XRCC2 and RAD51C. RAD51D',s expressionpattern and sequence similarity to other RAD51 family members most likely makes itpart of a complex of proteins required for DNA repair and meiotic recombination. Alternate Names: anti-RAD51L3 antibody, anti-RAD51-like 3 (S. cerevisiae) antibody, anti-TRAD antibody,anti-R51H3 antibody, anti-HsTRAD antibody, anti-RAD51D antibody, anti-recombinationrepair protein antibody, anti-DNA repair protein RAD51 homolog 4 antibody.
Gene ID 5892
Application Notes Suggested working dilutions: Western Blot 1:1,000
Restrictions For Research Use only
Format Liquid
Concentration 1.9 mg/ml
Buffer PBS. Preservative: 0.05% sodium azide.
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-RAD51 Homolog D (S. Cerevisiae) (RAD51D) antibody Western blot detection of Rad51D (35 kDa) from Hela S3 cell extract using ABIN151188.
General Schild, Lio, Collins et al.: "Evidence for simultaneous protein interactions between human Rad51 paralogs." in: The Journal of biological chemistry, Vol. 275, Issue 22, pp. 16443-9, 2000 (PubMed).

Hinz, Tebbs, Wilson et al.: "Repression of mutagenesis by Rad51D-mediated homologous recombination." in: Nucleic acids research, Vol. 34, Issue 5, pp. 1358-68, 2006 (PubMed).

Wiese, Hinz, Tebbs et al.: "Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination." in: Nucleic acids research, Vol. 34, Issue 9, pp. 2833-43, 2006 (PubMed).

Chattopadhyay, Das, Maiti et al.: "Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7066-80, 2008 (PubMed).

Shammas, Shmookler Reis, Koley et al.: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." in: Blood, Vol. 113, Issue 10, pp. 2290-7, 2009 (PubMed).

Hosts (28), (13), (5)
Reactivities (44), (3), (3), (1)
Applications (41), (17), (7), (5), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1)
Epitopes (4), (3), (3), (2), (2), (1), (1)
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