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Details for Product No. ABIN250565

BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

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Antigen
Synonyms BACH1, FANCJ, OF, 3110009N10Rik, 8030460J03Rik, Bach1, FACJ, Fancj, MGC68622, BRIP1, fancj, si:ch211-158l18.1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN250565
Quantity 25 µL
Price
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Immunogen Partial Brip1 protein peptide.
Clone Pp15-IB4
Isotype IgG1
Specificity This antibody is specific for Brip1 /FANCJ. Species Reactivity: Human. Other species have not been tested.
Cross-Reactivity Human
Purification Ascites
Alternative Name BRIP1 / FANCJ
Background BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recentlybeen found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJhas a function in the Fanconi anemia pathway that is independent of BRCA1 anddownstream of FANCD2 activation. (1-4). Alternate Names: anti-FANCJ protein antibody, anti-BACH 1 antibody, anti-BACH1 BRIP1 antibody,anti-BRIP 1 antibody, anti-BRAC 1 Associated C Terminal Helicase 1 antibody,anti-BRCA 1 Interacting Protein 1 antibody, anti- Fanconi anemia group J protein.
Gene ID 83990
Application Notes Suggested working dilutions: Western Blot 1:500-1:1,000. Positive Controls: HeLa whole and nuclear extracts, Raji whole extracts
Restrictions For Research Use only
Format Liquid
Buffer Preservative: 0.02% sodium azide.
Preservative Sodium azide
Storage 4 °C
Cantor, Bell, Ganesan et al.: "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function." in: Cell, Vol. 105, Issue 1, pp. 149-60, 2001 (PubMed).

Kim, Kee, Gurtan et al.: "Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24." in: Blood, Vol. 111, Issue 10, pp. 5215-22, 2008 (PubMed).

Alternatives for antigen "BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)", type "Antibodies"
Hosts (43), (17), (1)
Reactivities (58), (28), (24), (12), (12), (12), (12), (12)
Applications (39), (20), (13), (12), (8), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (12), (6), (4), (3), (2), (2), (2), (1), (1), (1)
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