DAF3 antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Alternatives Immunoprecipitation (IP), Western Blotting (WB)
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| Catalog no. |
ABIN250572 |
| Quantity |
25 µl (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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DAF-3
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Gene ID
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180431
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Immunogen
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A synthetic peptide made to the C-terminus (within residues 700-796) of the C.elegansDAF-3 protein.
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Format
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Serum
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Description
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Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smadproteins, which transcriptionally activate target genes. In Caenorhabditis elegans(C.elegans), defects in a TGF-beta-related pathway cause a reversible developmentalarrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere withdauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized,rather than activated, by a TGF-beta pathway. Alternate Names: anti-Abnormal dauer formation protein 3 antibody, anti-isoform c antibody, anti-DAF3antibody, anti-DAF 3 antibody.
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Specificity
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Species Reactivity: ABIN151423 can be used to detect C. elegans DAF-3 protein. Localization: Nuclear.
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Application Notes
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Western Blot 1:1,000-1:5,000
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Purification
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Serum
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Buffer
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Preservative: 0.05% sodium azide.
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Storage
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Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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Restrictions
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For Research Use only
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Deplancke, Mukhopadhyay, Ao et al.: "A gene-centered C. elegans protein-DNA interaction network." in: Cell, Vol. 125, Issue 6, pp. 1193-205, 2006 (PubMed).
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Alternatives for antigen "DAF3", type "Antibodies"