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PIP2 antibody

Antigen

PIP2
Clonality Monoclonal (2C11)
Host

Mouse
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB), ELISA
3 references available
Catalog no. ABIN251196
Quantity 0.1 mg  (1.6 mg/ml)
Price Product not available in this region.
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Additional Information
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Immunogen Liposomes (prepared in PBS with lipid A, phosphatidylcholine (PC) and cholesterol)containing synthetic di-palmitoyl PtdIns(4,5)P2.
Isotype IgM
Clone 2C11
Description Phosphatidylinositol 4,5-biphosphate (PIP2) has been implicated in a variety of cellularprocesses, including synaptic vesicle recycling. Alternate Names: anti-Phosphatidylinositol biphosphate antibody, anti-Phosphatidylinositol diphosphateantibody, anti-PIP 2 antibody.
Specificity Reacts with PtdIns(4,5)P2, Ptd(4)P and Ptd(3,4,5)P3. Species Reactivity: Human.

Application Details
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Concentration 1.6 mg/ml
Buffer PBS. Preservative: No Preservative.
Research Area Signaling
Restrictions For Research Use only

Publications
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Thomas, Steel, Prestwich et al.: "Generation of phosphatidylinositol-specific antibodies and their characterization." in: Biochemical Society transactions, Vol. 27, Issue 4, pp. 648-52, 2000 (PubMed).

Osborne, Thomas, Gschmeissner et al.: "Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing." in: Journal of cell science, Vol. 114, Issue Pt 13, pp. 2501-11, 2001 (PubMed).

Evans, Walker: "Endothelin-1 mobilizes profilin-1-bound PIP2 in cardiac muscle." in: Experimental biology and medicine (Maywood, N.J.), Vol. 231, Issue 6, pp. 882-7, 2006 (PubMed).