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BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

Antigen

BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)
Synonyms OF, BACH1, FANCJ, FLJ90232, MGC126521, MGC126523, Bach1, 3110009N10Rik, 8030460J03Rik, MGC68622, BRIP1, fancj, si:ch211-158l18.1
Clonality Monoclonal (GO11-3E6)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
2 references available
Catalog no. ABIN251429
Quantity 25 µl  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name BRIP1 / FANCJ
Gene ID 83990
Immunogen Fusion protein 647-1043 of human Brip1.
Cross-Reactivity Human
Isotype IgG1
Clone GO11-3E6
Description BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recentlybeen found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJhas a function in the Fanconi anemia pathway that is independent of BRCA1 anddownstream of FANCD2 activation. (1-4). Alternate Names: anti-FANCJ protein antibody, anti-BACH 1 antibody, anti-BACH1 BRIP1 antibody,anti-BRIP 1 antibody, anti-BRAC 1 Associated C Terminal Helicase 1 antibody,anti-BRCA 1 Interacting Protein 1 antibody, anti- Fanconi anemia group J protein.
Specificity This antibody is specific for Brip1. Species Reactivity: ABIN151815 recognizes human Brip1.

Application Details
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Application Notes Suggested working dilutions: Western Blot 1:500. Positive Controls: HeLa whole and nuclear extracts, Raji whole cell extracts.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Ohira, Seki, Nagase et al.: "Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1." in: Genomics, Vol. 47, Issue 2, pp. 300-6, 1998 (PubMed).

Cantor, Bell, Ganesan et al.: "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function." in: Cell, Vol. 105, Issue 1, pp. 149-60, 2001 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)", type "Antibodies"
Hosts Rabbit (34), Mouse (8), Chicken (1)
Reactivities Human (43), Mouse (Murine) (24), Rat (Rattus) (24), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Horse (Equine) (19), Pig (Porcine) (19)
Applications Immunofluorescence (IF) (21), Western Blotting (WB) (19), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes C-Term (4), pSer990 (4), AA 1233-1249 (2), N-Term (2), AA 92-104 (1), pThr401 (1)