Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) antibody

Antigen: Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA)

Synonyms: RP-C, PP2Ac, PP2CA, PP2A, R75353, Pp2a1, PPP2CA, B56G, PR61G, MGC23064, C85228, AI060890, AW545884, mKIAA0044, D12Bwg0916e, 2610043M05Rik, 2700063L20Rik, b56g, MGC76127, PPP2R5C, MGC53697, MGC81679, MGC143298, si:dkey-241l7.9, DKFZp459H033

Clonality: Monoclonal (TQ11-1G6)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP), Western Blotting (WB)

Catalog no.: ABIN251648

Additional Information

Alternative name: PPP2R5C

Gene ID: 5527

Immunogen: Human PP2A B56 gamma 3 (PPP2R5C transcript variant 1).

Cross-Reactivity: Human, Mouse (Murine)

Isotype: IgG1

Clone: TQ11-1G6

Description: Phosphatases are involved in the regulation of MAP kinases. Protein phosphatase 2A(PP2A) is a critical component of the pathway responsible for p38 MAPK up-regulationof SERT catalytic activity. Alternate Names: anti-PP2A antibody, anti-Protein Phosphatase 2A antibody, anti-PP2CB antibody,anti-PPP2CB antibody, anti-Protein Phosphatase 2 antibody, anti-Catalytic Subunit BetaIsoform antibody, anti-Serine/threonine-protein phosphatase 2A antibody,anti-PPP2R5C antibody, anti-B', alpha regulatory subunit antibody, anti-B56Gantibody, anti-IMYPNO1 antibody, anti-KIAA0044 antibody, anti-MGC23064 antibody,anti-PP2A B subunit B', gamma isoform antibody, anti-PP2A B subunit B56gamma isoform antibody, anti-PP2A B subunit PR61 gamma isoform antibody,anti-PP2A B subunit R5 gamma isoform antibody, anti-PP2A subunit B B gammaisoform antibody, anti-PP2A subunit B B55 gamma isoform antibody, anti-PP2A subunitB PR55 gamma isoform antibody, anti-PP2A subunit B R2 gamma isoform antibody,anti-PR61G antibody, anti-Protein phosphatase 2 regulatory subunit B (B56) gammaisoform antibody, anti-Renal carcinoma antigen NY REN 29 antibody,anti-Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gammaisoform antibody, anti-Serine/threonine protein phosphatase 2A 56 kDa regulatorysubunit gamma isoform antibody.

Specificity: This antibody is specific for PP2A (B56 gamma 3 subunit) protein. This antibody doesnot recognize the B56 gamma 1 isoform of PP2A. Species Reactivity: Human and mouse. Other species have not been tested.

Synonyms: RP-C, PP2Ac, PP2CA, PP2A, R75353, Pp2a1, PPP2CA, B56G, PR61G, MGC23064, C85228, AI060890, AW545884, mKIAA0044, D12Bwg0916e, 2610043M05Rik, 2700063L20Rik, b56g, MGC76127, PPP2R5C, MGC53697, MGC81679, MGC143298, si:dkey-241l7.9, DKFZp459H033

Application Details

Application Notes: By Western blot, this antibody recognizes overexpressed hPP2A B56gamma3 protein intransfected cells. Bands at ~50 and 35 kDa may also be seen. Western Blot analysis ofendogenous samples is not recommended due to high background. Has been shown towork effectively for immunoprecipitation, see Lin et al.Suggested working dilutions: *Western Blot - 1:1,000 (on transfected cell lysates).Immunoprecipitation - See Lin et al

Concentration: 2 mg/ml

Buffer: Preservative: Sodium Azide.

Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Research Area: Signaling

Restrictions: For Research Use only

Images

anti-Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) antibody

Publications

Kumamoto: "A contact-activated kinase signals Candida albicans invasive growth and biofilm development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 15, pp. 5576-81, 2005 (PubMed).

Lin, Bassik, Suh et al.: "PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23003-12, 2006 (PubMed).