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Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) antibody

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Synonyms b56g, ppp2r5c, si:dkey-241l7.9, 2610043M05Rik, 2700063L20Rik, AI060890, AW545884, C85228, D12Bwg0916e, mKIAA0044, B56G, PR61G
Human, Mouse (Murine)
(54), (19), (19), (1), (1)
(43), (10), (1)
Clonality (Clone)
Monoclonal ()
(4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunoprecipitation (IP), Western Blotting (WB)
(40), (16), (11), (8), (3), (3), (1)
Pubmed 2 references available
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Quantity 25 μL
Shipping to United States ( )
Immunogen Human PPP2R5C
Clone TQ11-1G6
Isotype IgG1 kappa
Specificity This is specific for PP2A (B56 gamma 3 subunit) protein. This does not recognize the B56 gamma 1 isoform of PP2A.
Purification Protein G purified
Alternative Name PPP2R5C (PPP2CA Antibody Abstract)
Background Phosphatases are involved in the regulation of MAP kinases. Protein phosphatase 2A(PP2A) is a critical component of the pathway responsible for p38 MAPK up-regulationof SERT catalytic activity. Alternate Names: anti-PP2A antibody, anti-Protein Phosphatase 2A antibody, anti-PP2CB antibody,anti-PPP2CB antibody, anti-Protein Phosphatase 2 antibody, anti-Catalytic Subunit BetaIsoform antibody, anti-Serine/threonine-protein phosphatase 2A antibody,anti-PPP2R5C antibody, anti-B', alpha regulatory subunit antibody, anti-B56Gantibody, anti-IMYPNO1 antibody, anti-KIAA0044 antibody, anti-MGC23064 antibody,anti-PP2A B subunit B', gamma isoform antibody, anti-PP2A B subunit B56gamma isoform antibody, anti-PP2A B subunit PR61 gamma isoform antibody,anti-PP2A B subunit R5 gamma isoform antibody, anti-PP2A subunit B B gammaisoform antibody, anti-PP2A subunit B B55 gamma isoform antibody, anti-PP2A subunitB PR55 gamma isoform antibody, anti-PP2A subunit B R2 gamma isoform antibody,anti-PR61G antibody, anti-Protein phosphatase 2 regulatory subunit B (B56) gammaisoform antibody, anti-Renal carcinoma antigen NY REN 29 antibody,anti-Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gammaisoform antibody, anti-Serine/threonine protein phosphatase 2A 56 kDa regulatorysubunit gamma isoform antibody.
Gene Symbol: PPP2R5C
Gene ID 5527, 19052
UniProt Q13362
Research Area Signaling
Pathways PI3K-Akt Signaling
Application Notes This PPP2R5C (TQ11-1G6) antibody is useful for Immunoprecipitation and Western blot. By Western blot, this antibody recognizes overexpressed PPP2R5C protein in transfected cells. Bands at ~50 and 35 kDa may also be seen. Western Blot analysis of endogenous samples is not recommended due to high background. Has been shown to work effectively for Immunoprecipitation, see Lin et al.
Recommended dilutions: Immunoprecipitation 1:10-1:500, Western Blot 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.
Supplier Images
Western Blotting (WB) image for anti-Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) antibody (ABIN251648) Detection of PP2A using ABIN151944.
Product cited in: Lin, Bassik, Suh et al.: "PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23003-12, 2006 (PubMed).

Kumamoto: "A contact-activated kinase signals Candida albicans invasive growth and biofilm development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 15, pp. 5576-81, 2005 (PubMed).

Catalog No. ABIN251648
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