Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) antibody

Details for Product No. ABIN251656
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Antigen
Synonyms OS-9, ERLEC2, zgc:153838
Reactivity
Human, Mouse (Murine)
(32), (25), (16), (12), (12), (2)
Host
Rabbit
(32)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(22), (13), (12), (12), (10), (9), (7), (5), (2)
Pubmed 1 reference available
Catalog no. ABIN251656
Quantity 0.1 mL
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Immunogen Synthetic peptide made to an internal portion of isoform 1 of the human protein (withinresidues 300-400). [Swiss-Prot# Q13438].
Specificity This antibody is specific for isoforms 1 and 2 of human OS-9. Species Reactivity: Reacts with human and mouse.
Cross-Reactivity Human, Mouse (Murine)
Purification Affinity Purified
Alternative Name OS9
Background OS9 is an ER glycoprotein found in the intralumenal level and highly expressed in tumortissue. The OS9 gene is transcriptionally induced upon activation of the Ire1/Xbp1ER-stress pathway. Alternate Names: anti-OS9 antibody, anti-Amplified in osteosarcoma antibody.
Gene ID 10956, 216440
UniProt Q13438
Research Area Cancer
Application Notes Suggested working dilutions: immunohistochemistry 0.5-1.0 ug/ml,immunofluorescence 0.2-1.0 ug/ml,Western Blot 0.2-1.0 ug/ml. Positive Controls: HEK293 postnuclear extracts.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/ml
Buffer Tris-citrate/phosphate [pH 7-8]. Preservative: 0.01% sodium azide.
Preservative Sodium azide
Storage 4 °C
Supplier Images
anti-Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) antibody Detection of OS-9.1 and OS-9.2 in total HEK293 cells, HEK293 cells expressing OS-9.1 or OS-9.2 by western analysis.
anti-Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) antibody (2) Immunoprecipitation of OS-9.1 and OS-9.2 in total HEK293 cells, HEK293 cells expressing OS-9.1 or OS-9.2.
anti-Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) antibody (3) Staining of OS-9 in mouse smooth muscle using ABIN251656.
General Bernasconi, Pertel, Luban et al.: "A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16446-54, 2008 (PubMed).

Hosts (32)
Reactivities (32), (25), (16), (12), (12), (2)
Applications (22), (13), (12), (12), (10), (9), (7), (5), (2)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (7), (5), (2), (1), (1), (1)
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