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Details for Product No. ABIN251656

Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9) antibody

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Antigen
Synonyms OS-9, ERLEC2, zgc:153838
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN251656
Quantity 0.1 mL
Price
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Immunogen Synthetic peptide made to an internal portion of isoform 1 of the human protein (withinresidues 300-400). [Swiss-Prot# Q13438].
Specificity This antibody is specific for isoforms 1 and 2 of human OS-9. Species Reactivity: Reacts with human and mouse.
Cross-Reactivity Human, Mouse (Murine)
Purification Affinity Purified
Alternative Name OS9
Background OS9 is an ER glycoprotein found in the intralumenal level and highly expressed in tumortissue. The OS9 gene is transcriptionally induced upon activation of the Ire1/Xbp1ER-stress pathway. Alternate Names: anti-OS9 antibody, anti-Amplified in osteosarcoma antibody.
Gene ID 10956, 216440
UniProt Q13438
Research Area Cancer
Application Notes Suggested working dilutions: immunohistochemistry 0.5-1.0 ug/ml,immunofluorescence 0.2-1.0 ug/ml,Western Blot 0.2-1.0 ug/ml. Positive Controls: HEK293 postnuclear extracts.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/ml
Buffer Tris-citrate/phosphate [pH 7-8]. Preservative: 0.01% sodium azide.
Preservative Sodium azide
Storage 4 °C
Bernasconi, Pertel, Luban et al.: "A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16446-54, 2008 (PubMed).

Alternatives for antigen "Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9)", type "Antibodies"
Hosts (34), (1)
Reactivities (34), (25), (16), (13), (12), (2), (1)
Applications (25), (14), (13), (13), (10), (9), (7), (5), (3), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (7), (7), (2), (2), (1), (1), (1)
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