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Chemokine (C-C Motif) Receptor 5 (CCR5) antibody

Antigen

Chemokine (C-C Motif) Receptor 5 (CCR5)
Synonyms CKR5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, FLJ78003, Ckr5, Cmkbr5, CCR5, CCR1-L, GPCR, MGC137803, CCR-5, AM4-7, CCR2, CCR5-L
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Flow Cytometry (FACS), Functional Studies (Func), ELISA
2 references available
Catalog no. ABIN251663
Quantity 25 µl  (0.5 mg/ml)  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name CD195 / CCR5
Gene ID 1234
Immunogen A synthetic peptide demonstrating a high affinity towards the monoclonal CCR5 2D7(see reference 2). This peptide is known as the 2D7-2SK peptide and consists of thefollowing residues: EWQKEGLVTLWLGGGGSC.
Cross-Reactivity Human, Monkey
Description CCR5 is a major coreceptor for human HIV infection. Alternate Names: anti-CCR5 antibody, anti-C-C CKR-5 antibody, anti-CC-CKR-5 antibody, anti-HIV-1fusion coreceptor antibody, anti-CHEMR13 antibody, anti-CD195 antigen antibody,anti-CMKBR5 antibody.
Specificity This antibody is specific for CCR5. It demonstrates 2D7-like reactivity. Species Reactivity: This antibody reacts with human and rhesus CCR5 protein.

Application Details
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Application Notes Suggested working dilutions: flow cytometry / FACS analysis 25 ug/ml,ELISA 1 ug/ml,In vitro assay
Concentration 0.5 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Research Area CD Antigens, Surface Receptors of Immune Cells, Chemokines, Receptors
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Trkola, Matthews, Gordon et al.: "A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor." in: Journal of virology, Vol. 73, Issue 11, pp. 8966-74, 1999 (PubMed).

Khurana, Kennedy, King et al.: "Identification of a linear peptide recognized by monoclonal antibody 2D7 capable of generating CCR5-specific antibodies with human immunodeficiency virus-neutralizing activity." in: Journal of virology, Vol. 79, Issue 11, pp. 6791-800, 2005 (PubMed).