BCL2 antibody (B-Cell CLL/lymphoma 2) (N-Term)

Details for Product anti-BCL2 Antibody No. ABIN256543, Supplier: Log in to see
Antigen
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • BCL2, apoptosis regulator
  • B cell leukemia/lymphoma 2
  • B-cell CLL/lymphoma 2a
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • bcl2a
  • BCL-2
Alternatives
anti-Human BCL2 antibody for Flow Cytometry
Epitope
N-Term, AA 61-76
164
77
66
64
44
31
25
25
23
21
18
15
15
15
13
13
13
11
9
9
6
6
6
5
5
5
5
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
1057
258
213
54
28
22
18
18
5
4
4
3
2
2
2
2
Host
Mouse
576
546
18
6
2
2
2
Clonality (Clone)
Monoclonal ()
Conjugate
This BCL2 antibody is un-conjugated
50
50
45
38
25
24
22
16
15
14
14
14
14
14
14
14
13
13
13
7
7
7
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
836
398
387
339
336
323
233
194
171
81
40
15
14
13
12
11
9
4
3
2
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen N-terminal, Amino acid residues 61-76 of mouse Bcl-2
Clone BCL-10C4
Isotype IgG1 kappa
Purification Protein A or G purified
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Gene Symbol: BCL2
Molecular Weight Theoretical MW: 26 kDa
Gene ID 596
UniProt P10417
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Western Blot 1:1000, Immunocytochemistry/Immunofluorescence 1-4 μg/mL, Immunoprecipitation 1:10-1:500Immunoprecipitation and Immunofluorescence use reported in literature. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS ( pH 7.2)
Buffer contains: 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 61-76), (N-Term) antibody (ABIN256543) Western blot analysis of extracts from mouse splenocytes using anti-Bcl-2, clone BCL/...
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 61-76), (N-Term) antibody (ABIN256543) Western Blot: Bcl-2 Antibody (BCL/10C4) [ABIN2565433] - Human pancreatic cancer cells...
Product cited in: Zuber, Rappaport, Luo, Wang, Chen, Vaseva, Shi, Weissmueller, Fellmann, Fellman, Taylor, Weissenboeck, Graeber, Kogan, Vakoc, Lowe: "An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance." in: Genes & development, Vol. 25, Issue 15, pp. 1628-40, 2011 (PubMed).

Hsu, Youle: "Nonionic detergents induce dimerization among members of the Bcl-2 family." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13829-34, 1997 (PubMed).

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