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CD8 alpha antibody (PerCP-Cy5.5)
CD8A
Reactivity: Human
FACS
Host: Mouse
Monoclonal
OKT8
PerCP-Cy5.5
Product Details anti-CD8 alpha Antibody (PerCP-Cy5.5)
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Target
See all CD8 alpha (CD8A) Antibodies
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Reactivity
All reactivities for CD8 alpha antibodies
Human
Host
All hosts for CD8 alpha antibodies
Mouse
Clonality
All clonalities for CD8 alpha antibodies
Monoclonal
Conjugate
All conjugates for CD8 alpha antibodies
This CD8 alpha antibody is conjugated to PerCP-Cy5.5
Application
All applications for CD8 alpha antibodies
Flow Cytometry (FACS)
Specificity
The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a tyPEI transmembrane glycoprotein of 32-34 kDa.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone
OKT8
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage
4 °C
Storage Comment
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target Details for CD8 alpha
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Target
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Alternative Name
CD8a (CD8A Products )
Synonyms
cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
Background
The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a tyPEI transmembrane glycoprotein of 32-34 kDa. CD8α is a member of the Ig superfamily, expressed as a homodimer (CD8αα) or as a heterodimer (CD8αβ). CD8+ αβ T lymphocytes express both CD8αα and CD8αβ, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes.OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.
Gene ID
925
UniProt
P01732
Pathways
TCR Signaling
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