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GAS6 antibody
GAS6
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GAS6 Antibody
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Target
See all GAS6 Antibodies
GAS6
(Growth Arrest-Specific 6 (GAS6))
Reactivity
All reactivities for GAS6 antibodies
Human, Mouse, Rat
Host
All hosts for GAS6 antibodies
Rabbit
Clonality
All clonalities for GAS6 antibodies
Polyclonal
Conjugate
All conjugates for GAS6 antibodies
This GAS6 antibody is un-conjugated
Application
All applications for GAS6 antibodies
Western Blotting (WB), ELISA
Specificity
GAS6 antibody is human, mouse and rat reactive. At least four isoforms of GAS6 are known to exist, this antibody will only detect the longest isoform.
Purification
GAS6 Antibody is affinity chromatography purified via peptide column.
Immunogen
GAS6 antibody was raised against a 19 amino acid peptide from near the amino terminus of human GAS6.
Isotype
IgG
Top Product
Discover our top product GAS6 Primary Antibody
Alternatives
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Application Details
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Application Notes
GAS6 antibody can be used for the detection of GAS6 by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
GAS6 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
GAS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for GAS6
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Target
GAS6
(Growth Arrest-Specific 6 (GAS6))
Alternative Name
GAS6 (GAS6 Products )
Synonyms
fj34a12 antibody, zgc:63860 antibody, wu:fj34a12 antibody, MGC68463 antibody, gas6 antibody, MGC83872 antibody, GAS6 antibody, Gas-6 antibody, AXLLG antibody, AXSF antibody, growth arrest specific 6 antibody, growth arrest-specific 6 antibody, growth arrest specific 6 L homeolog antibody, growth arrest specific 6 S homeolog antibody, GAS6 antibody, gas6 antibody, gas6.L antibody, gas6.S antibody, Gas6 antibody
Background
The growth arrest-specific 6 (GAS6) protein is a gamma-carboxyglutamic acid (Gla)-containing protein and a member of a family of plasma vitamin K-dependent proteins. GAS6 is involved in vascular homeostasis, cell proliferation, apoptosis, leukocyte migration, and platelet aggregation (1,2). GAS6 is the ligand for the type I transmembrane receptor tyrosine kinase receptors Tyro3, Axl, and Mer (3). This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker (4). Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia (2).
Molecular Weight
Predicted: 75 kDa Observed: 75 kDa
Gene ID
2621
NCBI Accession
NP_000811
UniProt
Q14393
Pathways
RTK Signaling , Carbohydrate Homeostasis , Production of Molecular Mediator of Immune Response
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