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GAS6 antibody

GAS6 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2568168
  • Target See all GAS6 Antibodies
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Reactivity
    • 41
    • 23
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 41
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 45
    • 4
    Polyclonal
    Conjugate
    • 26
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAS6 antibody is un-conjugated
    Application
    • 45
    • 13
    • 13
    • 12
    • 12
    • 7
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB), ELISA
    Specificity
    GAS6 antibody is human, mouse and rat reactive. At least four isoforms of GAS6 are known to exist, this antibody will only detect the longest isoform.
    Purification
    GAS6 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    GAS6 antibody was raised against a 19 amino acid peptide from near the amino terminus of human GAS6.
    Isotype
    IgG
    Top Product
    Discover our top product GAS6 Primary Antibody
  • Application Notes
    GAS6 antibody can be used for the detection of GAS6 by Western blot at 1 - 2 μ,g/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    GAS6 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    GAS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Alternative Name
    GAS6 (GAS6 Products)
    Synonyms
    fj34a12 antibody, zgc:63860 antibody, wu:fj34a12 antibody, MGC68463 antibody, gas6 antibody, MGC83872 antibody, GAS6 antibody, Gas-6 antibody, AXLLG antibody, AXSF antibody, growth arrest specific 6 antibody, growth arrest-specific 6 antibody, growth arrest specific 6 L homeolog antibody, growth arrest specific 6 S homeolog antibody, GAS6 antibody, gas6 antibody, gas6.L antibody, gas6.S antibody, Gas6 antibody
    Background
    The growth arrest-specific 6 (GAS6) protein is a gamma-carboxyglutamic acid (Gla)-containing protein and a member of a family of plasma vitamin K-dependent proteins. GAS6 is involved in vascular homeostasis, cell proliferation, apoptosis, leukocyte migration, and platelet aggregation (1,2). GAS6 is the ligand for the type I transmembrane receptor tyrosine kinase receptors Tyro3, Axl, and Mer (3). This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker (4). Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia (2).
    Molecular Weight
    Predicted: 75 kDa

    Observed: 75 kDa
    Gene ID
    2621
    NCBI Accession
    NP_000811
    UniProt
    Q14393
    Pathways
    RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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