The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
OSR1 (phospho Thr185) antibody was raised against a peptide sequence around phosphorylation site of threonine185 (R-K-T (p)-F-V) derived from Human OSR1.
Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress