Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) antibody

Details for Product No. ABIN257782
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Antigen
Synonyms PRL3, PRL-3, PRL-R, zgc:77109, wu:fc54b05, wu:fv52d11, prl-3, prl3, ptpcaax3, AV088979, Prl-3, pPtp4a3, PTP4A3
Reactivity
Human
(52), (28), (16), (13), (13), (2), (1), (1), (1)
Host
Goat
(44), (6), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(43), (15), (10), (5), (4), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN257782
Quantity 0.1 mg
Price
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  • +1 404 474 4654
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Immunogen Synthetic peptide with sequence NRPAPVEVSYKHMR, representing the N Terminusfrom the second Met of the protein (residues 5-18 according to NP_009010,NP_116000. Reference Sequence: NP_009010, NP_116000.
Isotype IgG
Specificity Species Reactivity: Reacts with human and mouse.
Cross-Reactivity Human
Purification Aff - Purified
Alternative Name PRL3 / PTP4A3
Background The protein encoded by this gene belongs to a small class of prenylated protein tyrosinephosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in avariety of cellular processes. This class of PTPs contain a PTP domain and acharacteristic C-terminal prenylation motif. Studies of this class of PTPs in micedemonstrated that they were prenylated proteins in vivo, which suggested theirassociation with cell plasma membrane. Overexpression of this gene in mammaliancells was reported to inhibit angiotensin-II induced cell calcium mobilization and promotecell growth. Two alternatively spliced variants exist. Alternate Names: anti-Potentially prenylated protein tyrosine phosphatase antibody, anti-PRL3 antibody,anti-PRLR antibody, anti-Protein tyrosine phosphatase 4a3 antibody, anti-Proteintyrosine phosphatase of regenerating liver 3 antibody, anti-Protein tyrosine phosphatasetype IVA member 3 antibody, anti-Protein tyrosine phosphatase type IVA protein 3antibody, anti-PRL-3 antibody.
Gene ID 11156
NCBI Accession NP_009010
Application Notes Suggested working dilutions: Western Blot 1.0-3.0ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline containing [pH7.3] with 0.5% BSA. Preservative: 0.02% Na azide.
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) antibody ABIN257782 staining (2µg/ml) of Human Pancreas lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
General Fagerli, Holt, Holien et al.: "Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells." in: Blood, Vol. 111, Issue 2, pp. 806-15, 2008 (PubMed).

Hosts (44), (6), (6)
Reactivities (52), (28), (16), (13), (13), (2), (1), (1), (1)
Applications (43), (15), (10), (5), (4), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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