PDX1 antibody (Pancreatic and Duodenal Homeobox 1) (AA 204-284)

Details for Product anti-PDX1 Antibody No. ABIN258270, Supplier: Log in to see
Antigen
  • ipf1
  • PDX1
  • Ad4BP
  • ELP
  • ELP-3
  • Ftz-F1
  • Ftzf1
  • SF-1
  • SF1
  • Ad4BP/SF-1
  • Ad4bp
  • Sf-1
  • GSF
  • IDX-1
  • IPF1
  • IUF1
  • MODY4
  • PDX-1
  • STF-1
  • IPF-1
  • Ipf1
  • Mody4
  • pdx-1
  • Idx1
  • Stf1
  • zgc:100874
  • XlHbox-8
  • xlhbox8
  • pancreatic and duodenal homeobox 1
  • nuclear receptor subfamily 5, group A, member 1
  • pdx1
  • PDX1
  • Nr5a1
  • Pdx1
Alternatives
anti-Rat (Rattus) PDX1 antibody for Chromatin Immunoprecipitation
Epitope
AA 204-284
27
27
26
19
18
13
6
6
6
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
203
56
40
7
6
6
5
5
4
3
2
2
2
2
2
1
1
Host
Rabbit
172
38
5
Clonality
Polyclonal
Conjugate
This PDX1 antibody is un-conjugated
11
11
11
11
10
10
1
1
1
1
1
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
140
112
67
35
25
20
16
13
5
5
5
2
1
1
1
Options
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Immunogen GST fusion protein corresponding to residues 204-284 of mouse PDX1.
Purification Unpurified
Alternative Name PDX-1/IPF1 (PDX1 Antibody Abstract)
Background Gene Symbol: PDX1
Molecular Weight Theoretical MW: 31 kDa
Gene ID 3651
Pathways Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
Application Notes Western Blot 1:1000-1:2000, Chromatin Immunoprecipitation 1:10-1:500, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer Whole Rabbit antisera with 30 % Glycerol
Buffer contains: 0.035 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C,-20 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-PDX1 antibody (Pancreatic and Duodenal Homeobox 1) (AA 204-284) (ABIN258270) Mouse pancreatic beta T cell lysate was probed with anti-PDX1 (1:20,000 dilution). Ar...
Product cited in: Perelis, Marcheva, Ramsey, Schipma, Hutchison, Taguchi, Peek, Hong, Huang, Omura, Allred, Bradfield, Dinner, Barish, Bass: "Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion." in: Science (New York, N.Y.), Vol. 350, Issue 6261, pp. aac4250, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Chromatin Immunoprecipitation

Schwitzgebel, Scheel, Conners, Kalamaras, Lee, Anderson, Sussel, Johnson, German: "Expression of neurogenin3 reveals an islet cell precursor population in the pancreas." in: Development (Cambridge, England), Vol. 127, Issue 16, pp. 3533-42, 2000 (PubMed).

Background publications Ahlgren, Jonsson, Jonsson, Simu, Edlund: "beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes." in: Genes & development, Vol. 12, Issue 12, pp. 1763-8, 1998 (PubMed).

Stoffers, Zinkin, Stanojevic, Clarke, Habener: "Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence." in: Nature genetics, Vol. 15, Issue 1, pp. 106-10, 1997 (PubMed).