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Details for Product No. ABIN258270

Pyruvate Dehydrogenase Complex, Component X (PDHX) antibody

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Synonyms E3BP, OPDX, PDX1, proX, DLDBP, E3bp, Pdx1, AI481367, Ac1164, zgc:66110, zgc:85977, MGC86218, PDHX, DDBDRAFT_0168431, DDBDRAFT_0230192, DDB_0168431, DDB_0230192
»Alternatives Mouse (Murine), Rat (Rattus)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN258270
Quantity 50 µL
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Immunogen GST fusion protein corresponding to residues 204-284 of mouse PDX1/IPF1.
Specificity Detects a band at approximately 35-40 kDa. Species Reactivity: Reacts with Mouse and Rat.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Serum
Alternative Name PDHX / PDX1
Background PDX1 (Pancrease/duodenum homeobox 1, Insulin promoter factor 1, IPF1,Islet/duodenum homeobox 1, IDX1, Somatatostatin transactivating factor 1, STF1,Insulin upstream factor 1, UUF1, Glucose-sensitive factor, GSF) activates transcriptionof the insulin and somatostain genes. PDX1 is required for maintaining thehormone-producing phenotype of the beta-cell. Alternate Names: anti-Glucose sensitive factor antibody, anti-GSF antibody, anti-IDX 1 antibody, anti-IDX1antibody, anti-Insulin promoter factor 1 antibody, anti-insulin promoter factor 1homeodomain transcription factor antibody, anti-insulin upstream factor 1 antibody,anti-IPF1 antibody, anti-Islet/duodenum homeobox 1 antibody, anti-IUF 1 antibody,anti-IUF1 antibody, anti-MODY4 antibody, anti-Pancreas/duodenum homeobox 1antibody, anti-PDX 1 antibody, anti-Somatostatin transactivating factor 1 antibody,anti-STF 1 antibody, anti-STF1 antibody.
Application Notes Suggested working dilutions: immunohistochemistry assay dependent ,Western Blot 1:1000 - 1:2000. Positive Controls: mouse pancreatic beta T cells
Restrictions For Research Use only
Format Liquid
Buffer 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 30% glycerol. Preservative: 0.05% sodium azide.
Preservative Sodium azide
Storage -20 °C
Stoffers, Zinkin, Stanojevic et al.: "Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence." in: Nature genetics, Vol. 15, Issue 1, pp. 106-10, 1997 (PubMed).

Ahlgren, Jonsson, Jonsson et al.: "beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes." in: Genes & development, Vol. 12, Issue 12, pp. 1763-8, 1998 (PubMed).

Alternatives for antigen "Pyruvate Dehydrogenase Complex, Component X (PDHX)", type "Antibodies"
Hosts (24), (5), (3)
Reactivities (32), (18), (15), (12), (1)
Applications (22), (16), (10), (10), (5), (4), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (1), (1), (1), (1)