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Pyruvate Dehydrogenase Complex, Component X (PDHX) antibody

Antigen

Pyruvate Dehydrogenase Complex, Component X (PDHX)
Synonyms E3BP, OPDX, PDX1, proX, DLDBP, E3bp, Pdx1, AI481367, Ac1164, MGC66110, zgc:66110, zgc:85977, MGC86218, PDHX, MGC143185
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
2 references available
Catalog no. ABIN258270
Quantity 50 µl
Price Product not available in this region.
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anti-Pyruvate Dehydrogenase Complex, Component X (PDHX) antibody

Additional Information
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Alternative name PDHX / PDX1
Immunogen GST fusion protein corresponding to residues 204-284 of mouse PDX1/IPF1.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Format Serum
Description PDX1 (Pancrease/duodenum homeobox 1, Insulin promoter factor 1, IPF1,Islet/duodenum homeobox 1, IDX1, Somatatostatin transactivating factor 1, STF1,Insulin upstream factor 1, UUF1, Glucose-sensitive factor, GSF) activates transcriptionof the insulin and somatostain genes. PDX1 is required for maintaining thehormone-producing phenotype of the beta-cell. Alternate Names: anti-Glucose sensitive factor antibody, anti-GSF antibody, anti-IDX 1 antibody, anti-IDX1antibody, anti-Insulin promoter factor 1 antibody, anti-insulin promoter factor 1homeodomain transcription factor antibody, anti-insulin upstream factor 1 antibody,anti-IPF1 antibody, anti-Islet/duodenum homeobox 1 antibody, anti-IUF 1 antibody,anti-IUF1 antibody, anti-MODY4 antibody, anti-Pancreas/duodenum homeobox 1antibody, anti-PDX 1 antibody, anti-Somatostatin transactivating factor 1 antibody,anti-STF 1 antibody, anti-STF1 antibody.
Specificity Detects a band at approximately 35-40 kDa. Species Reactivity: Reacts with Mouse and Rat.

Application Details
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Application Notes Suggested working dilutions: immunohistochemistry assay dependent ,Western Blot 1:1000 - 1:2000. Positive Controls: mouse pancreatic beta T cells
Purification Serum
Buffer 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 30% glycerol. Preservative: 0.05% sodium azide.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Restrictions For Research Use only

Publications
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Stoffers, Zinkin, Stanojevic et al.: "Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence." in: Nature genetics, Vol. 15, Issue 1, pp. 106-10, 1997 (PubMed).

Ahlgren, Jonsson, Jonsson et al.: "beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes." in: Genes & development, Vol. 12, Issue 12, pp. 1763-8, 1998 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Pyruvate Dehydrogenase Complex, Component X (PDHX)", type "Antibodies"
Hosts Rabbit (31), Goat (3)
Reactivities Human (33), Mouse (Murine) (22), Rat (Rattus) (22), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications ELISA (17), Immunofluorescence (IF) (17), Western Blotting (WB) (15), Immunohistochemistry (IHC) (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (3), N-Term (2), Thr11 (1), pSer66 (1)