Leucine-Rich Repeat Kinase 2 (LRRK2) antibody

Details for Product No. ABIN258600
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Antigen
Synonyms PARK8, RIPK7, ROCO2, AURA17, DARDARIN, Gm927, cI-46, AW561911, 4921513O20Rik, 9330188B09Rik, D630001M17Rik, LRRK2
Reactivity
Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(135), (73), (72), (34), (13), (13), (2)
Host
Rabbit
(97), (50), (5), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(127), (45), (39), (36), (33), (20), (15), (12), (11), (8), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN258600
Quantity 25 µL
Price
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Immunogen A synthetic peptide made to a C-terminal region, within residues 2480-2527 of thehuman LRRK2 protein, conjugated to KLH. [Swiss-Prot# Q5S007].
Specificity Species Reactivity: Reacts with human, rat and mouse. Localization: Cytoplasm. Membrane, Peripheral membrane protein.
Cross-Reactivity Human, Mouse (Murine)
Purification Affinity Purified
Alternative Name PARK8 / LRRK2
Background This gene is a member of the leucine-rich repeat kinase family and encodes a proteinwith an ankryin repeat region, a leucine-rich repeat (LRR) domain, a GTPase domain, akinase domain, and a WD40 domain. The protein is present largely in the cytoplasm, butalso associates with lipid membranes. Mutations in this gene have been geneticallylined to late-onset, Lewy body Parkinson disease. Alternate Names: anti-LRRK-2 antibody, anti-LRRK 2 antibody, anti-PARK8 antibody, anti-ROCO2antibody, anti-Dardarin antibody. Related Diseases: Parkinson',s Disease, Lewy Body Disease
Gene ID 120892
Application Notes Suggested working dilutions: Immunohistochemistry-Frozen 1:100-1:200. Positive Controls: Human lymphoblasts for IHC and human and mouse brain for Western blot
Restrictions For Research Use only
Format Liquid
Buffer Tris-glycine. Preservative: 0.05% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) antibody ABIN258599 in increasing amounts of human lymphoblast
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) antibody (2) anti-Leucine-Rich Repeat Kinase 2 (LRRK2) antibody (Image 2)
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) antibody (3) DAB Immunostaining in mouse brainstem
General Melrose, Kent, Taylor et al.: "A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease." in: Neuroscience, Vol. 147, Issue 4, pp. 1047-58, 2007 (PubMed).

Hosts (97), (50), (5), (3), (1)
Reactivities (135), (73), (72), (34), (13), (13), (2)
Applications (127), (45), (39), (36), (33), (20), (15), (12), (11), (8), (2), (1), (1), (1), (1)
Conjugates (7), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (32), (20), (18), (18), (12), (12), (8), (6), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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