Erythrocyte Membrane Protein Band 4.1 Like 3 (EPB41L3) antibody

Details for Product No. ABIN258877
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms 4.1B, DAL-1, DAL1, DAL1P, Dal1, Epb41l3, NBL3, Epb4.1l3, Kiaa0987, EPB4.1L3, EPB41L1
Reactivity
Human
(32), (20), (20), (14), (12), (12), (12), (7)
Host
Rabbit
(24), (6), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(23), (10), (9), (4), (3), (2), (1)
Pubmed 2 references available
Catalog no. ABIN258877
Quantity 25 µL
Price
Contact our Customer Service for availability and price in your country.
Shipping to United States (Change)
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide made to an internal region of the human protein (within residues400-500). [Swiss-Prot# Q9Y2J2].
Specificity Species Reactivity: Reacts with human, mouse, rat and Xenopus. Theoretical Molecular Weight: 120 kDa (isoform A), 96 kDa (isorform B).
Cross-Reactivity Human, Mouse (Murine)
Purification Aff - Purified
Alternative Name EPB41L3
Background Protein 4.1B is a member of a family of similar proteins whose expression is frequentlylost in a variety of human tumors, including meningiomas, non-small-cell lung cancers,and breast carcinomas and is frequently down-regulated in human clinical prostatecancer. Studies have shown that Protein 4.1B normally triggers death in metastaticcells, thereby preventing cancer from spreading. A clinical test for Protein 4.1B activitycould be useful in assessing the metastatic potential of prostate cancers. Alternate Names: anti-4.1B antibody, anti-Differentially expressed in adenocarcinoma of the lung protein 1antibody, anti-DAL-1 antibody, anti-EPB41L3 antibody, anti-DAL1 antibody,anti-KIAA0987 antibody. Related Diseases: Prostate Cancer
Gene ID 23136
Research Area Cancer, Cytoskeleton, Microfilaments
Application Notes Suggested working dilutions: Western Blot 2 ug/ml. Positive Controls: Human and mouse brain lysate, HeLa whole cell lysate
Restrictions For Research Use only
Format Liquid
Concentration 1.15 mg/ml
Buffer PBS, 30% glycerol. Preservative: 0.1% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Erythrocyte Membrane Protein Band 4.1 Like 3 (EPB41L3) antibody Detection of Band 4.1 in HeLa whole cell lysate using ABIN258876.
anti-Erythrocyte Membrane Protein Band 4.1 Like 3 (EPB41L3) antibody (2) Detection of Band 4.1 in mouse brain lysate using ABIN258876.
General McCarty, Cook, Hynes: "An interaction between {alpha}v{beta}8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 38, pp. 13479-83, 2005 (PubMed).

Wong, Haack, Kissil et al.: "Protein 4.1B suppresses prostate cancer progression and metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 31, pp. 12784-9, 2007 (PubMed).

Hosts (24), (6), (5)
Reactivities (32), (20), (20), (14), (12), (12), (12), (7)
Applications (23), (10), (9), (4), (3), (2), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (5), (3), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top