Striatin, Calmodulin Binding Protein 3 (STRN3) antibody

Details for Product No. ABIN259103
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Antigen
Synonyms SG2NA, Gs2na, Sg2na, STRN3, GS2NA, KIAA1333, MGC175239, id:ibd1241, wu:fc02f06, si:dz115o7.2, si:dz234g15.7, si:busm1-115o7.2, MGC145300, strn, MGC80575
Reactivity
Human
(17), (14), (13), (12), (12), (12), (12)
Host
Mouse
(14), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(10), (9), (5), (4), (2), (2), (1)
Pubmed 3 references available
Catalog no. ABIN259103
Quantity 0.1 mL
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Immunogen Synthetic peptide made to an internal portion of the human protein (within residues200-300). [Swiss-Prot# Q13033].
Clone S68
Isotype IgG1
Specificity This antibody does not cross-react with Striatin. Species Reactivity: Human, mouse and rat. Localization: Cytoplasm and membrane.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Ascites
Alternative Name Striatin-3 / SG2NA
Background SG2NA was identified as a human cancer autoantigen and has now been implicated invesicular trafficking and signal transduction. It is highly related to striatin and zinedin. Itis a scaffolding protein that binds PP2A A and C subunits as well as the human homologof the yeast protein, Mob1, which has been implicated in control of mitotic progression inyeast. It also binds calmodulin and appears to modulate PP2A activity. Alternate Names: anti-Striatin-3 antibody, anti- Cell-cycle autoantigen SG2NA antibody, anti-S/G2 antigenantibody, anti-STRN3 antibody, anti-GS2NA antibody.
Application Notes Suggested working dilutions: immunofluorescence 1:5000,Western Blot 1:250-1:2000
Restrictions For Research Use only
Format Liquid
Buffer Preservative: Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Supplier Images
anti-Striatin, Calmodulin Binding Protein 3 (STRN3) antibody Detection of SG2NA in NIH3T3 cell lysates using ABIN259103.
anti-Striatin, Calmodulin Binding Protein 3 (STRN3) antibody (2) Immunofluorescent staining of NIH3T3 cells using ABIN259103.
General Moreno, Park, Nelson et al.: "WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5257-63, 2000 (PubMed).

Yu, Du, Moreno et al.: "Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen." in: Molecular biology of the cell, Vol. 12, Issue 1, pp. 185-99, 2001 (PubMed).

Moreno, Lane, Pallas: "A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24253-60, 2001 (PubMed).

Hosts (14), (5)
Reactivities (17), (14), (13), (12), (12), (12), (12)
Applications (10), (9), (5), (4), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1)
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