Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) antibody

Antigen: Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1)

Synonyms: Nac1, Btbd14b, 2010001H03Rik, 4930511N13Rik, NAC1, BEND8, NAC-1, BTBD14B, FLJ37383, Nac-1

Clonality: Monoclonal (3)

Host: Mouse

Reactivity: Human

Application: Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN259549

Additional Information

Alternative name: NACC1 / BTBD14B

Gene ID: 112939

UniProt: Q96RE7

Immunogen: Recombinant human NAC1 protein.

Cross-Reactivity: Human

Clone: 3

Description: The BTB/POZ gene family shares a conserved BTB/POZ protein-protein interactionmotif at the N terminus that mediates homodimer or heterodimer formation. NAC1, amember of this family, has been found to be overexpressed in ovarian cancer. Thisprotein appears to play a critical role in tumorigenesis and in the growth and survival oftumor cells. Alternate Names: anti-BTB/POZ domain-containing protein 14B antibody, anti-Nucleus accumbens-1antibody, anti-BTBD14B antibody, anti-NAC1 antibody, anti-NAC-1 antibody, anti-NAC 1antibody. Related Diseases: Ovarian Cancer

Specificity: Species Reactivity: This antibody reacts with human. Localization: Nuclear.

Application Details

Application Notes: Suggested working dilutions: immunofluorescence 1:100-1:500, dilution,Western Blot 0.3 ug/ml,Immunocytochemistry 1:100,Immunohistochemistry-Paraffin 1:100

Concentration: 0.82 mg/ml

Purification: Purified

Buffer: Tris-glycine, 150mM NaCl. Preservative: 0.05% sodium azide.

Storage: Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thawcycles.

Restrictions: For Research Use only

Images

Detection of NAC-1 in HeLa nuclear extracts using ABIN259549.

Nuclear staining of paraffin-embedded ovarian cancer cells using ABIN259549.

Publications

Nakayama, Nakayama, Davidson et al.: "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18739-44, 2006 (PubMed).