Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) antibody

Details for Product No. ABIN259556
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Antigen
Synonyms 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hsd11, hsd11b, LRRGT00065, Hsd11b1
Reactivity
Human, Monkey, Baboon
(81), (37), (35), (15), (13), (13), (1), (1), (1), (1)
Host
Mouse
(64), (11), (11), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(56), (35), (20), (19), (11), (8), (6), (5), (5), (2), (2), (2), (2), (1)
Pubmed 2 references available
Catalog no. ABIN259556
Quantity 0.1 mL
Price
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen JEG Choriocarcinoma cells.
Clone FDO66Q
Isotype IgG1
Specificity Species Reactivity: Human, Baboon and Marmoset. Other species have not been tested. Localization: Membrane.
Cross-Reactivity Human
Purification Purified
Alternative Name 3-beta-HSD1 / HSD3B1
Background 3-beta hydroxysteroid dehydrogenase (HSD3B1) is a bifunctional enzyme involved inthe oxidative conversion of ketosteroids that plays an important role in the synthesis ofall steroid hormones. There are two HSD3B1 proteins, designated type I and type II, thatare expressed by different genes and function in different areas of the body. HSD3B1has also been shown to be a highly specific and sensitive trophoblast-associated marker(Mao et. al). Alternate Names: anti-3-beta-HSD I antibody, anti-Trophoblast antigen FDO161G antibody, anti-HSD3B1antibody, anti-3BH antibody, anti-HSDB3A antibody, anti-3BHSD antibody.
Gene ID 3283
Application Notes Suggested working dilutions: immunofluorescence 10-20 ug/ml,Immunocytochemistry 10-20 ug/ml,Immunohistochemistry-Paraffin 10-20 ug/ml,Immunohistochemistry-Frozen 10-20 ug/ml. Positive Controls: Human placental villi
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/ml
Buffer Tris-glycine, 150mM NaCl. Preservative: 0.05% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) antibody Staining of placental villi using ABIN259556.
General Mueller, Hawes, Wright et al.: "Isolation of fetal trophoblast cells from peripheral blood of pregnant women." in: Lancet, Vol. 336, Issue 8709, pp. 197-200, 1990 (PubMed).

Mao, Kurman, Jeng et al.: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, 2008 (PubMed).

Hosts (64), (11), (11), (4)
Reactivities (81), (37), (35), (15), (13), (13), (1), (1), (1), (1)
Applications (56), (35), (20), (19), (11), (8), (6), (5), (5), (2), (2), (2), (2), (1)
Conjugates (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (12), (6), (4), (4), (4), (3), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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