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Transferrin Receptor (p90, CD71) (TFRC) antibody (FITC)

Details for Product No. ABIN264290, Supplier: Log in to see
Antigen
  • TFRC
  • tfr
  • cd71
  • tfr1
  • trfr
  • LOC100219280
  • 2610028K12Rik
  • AI195355
  • AI426448
  • AU015758
  • CD71
  • E430033M20Rik
  • Mtvr-1
  • Mtvr1
  • TFR
  • TFR1
  • TR
  • Trfr
  • p90
  • T9
  • TRFR
  • transferrin receptor (p90, CD71)
  • transferrin receptor
  • TFRC
  • tfrc
  • LOC100219280
  • Tfrc
Alternatives
anti-Human Transferrin Receptor (p90, CD71) antibody for Immunocytochemistry
Reactivity
Human
293
118
34
11
4
4
4
4
4
2
2
2
Host
Mouse
237
87
72
9
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
59
48
38
20
7
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
273
128
88
84
58
44
35
18
16
11
7
5
4
3
3
2
2
1
1
1
1
1
1
Options
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Immunogen Derived from hybridization of mouse Sp2/0 myeloma cells and spleen cells from miceimmunized with human peripheral blood.
Clone BGX-24
Isotype IgG1
Characteristics Synonyms: TfR1, p90, Transferrin receptor protein 1
Alternative Name CD71 / TFRC (TFRC Antibody Abstract)
Background CD71 antigen expression is low on normal resting lymphocytes and is expressed on all cells upon activation. The transferrin receptor is essential for iron transport into proliferating cells, such as mitogen-activated and alloantigen-activated lymphoblasts. The transferrin receptor is also present on early erythroid cells but is lost as reticulocytes differentiate into mature erythrocytes.Synonyms: TfR1, Transferrin receptor protein 1, p90
UniProt P02786
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Transition Metal Ion Homeostasis
Application Notes Flow Cytometry. Study of discrimination of activated lymphocytes from resting lymphocytes. Study of erythropoiesis. Analysis of metabolic activation or cellular proliferation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Protocol PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze.
Restrictions For Research Use only
Buffer PBS containing 0.2 % protein carrier and 0.08 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. Do Not Freeze!
Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Loken, Shah, Dattilio, Civin: "Flow cytometric analysis of human bone marrow: I. Normal erythroid development." in: Blood, Vol. 69, Issue 1, pp. 255-63, 1987 (PubMed).

Phillips, Le, Lanier: "Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens." in: The Journal of experimental medicine, Vol. 159, Issue 4, pp. 993-1008, 1984 (PubMed).

Jefferies, Brandon, Hunt, Williams, Gatter, Mason: "Transferrin receptor on endothelium of brain capillaries." in: Nature, Vol. 312, Issue 5990, pp. 162-3, 1984 (PubMed).

Judd, Poodry, Strominger: "Novel surface antigen expressed on dividing cells but absent from nondividing cells." in: The Journal of experimental medicine, Vol. 152, Issue 5, pp. 1430-5, 1981 (PubMed).