Transferrin Receptor (p90, CD71) (TFRC) antibody

Details for Product No. ABIN264291
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Antigen
Synonyms TFRC, tfr, cd71, tfr1, trfr, LOC100219280, 2610028K12Rik, AI195355, AI426448, AU015758, CD71, E430033M20Rik, Mtvr-1, Mtvr1, TFR, TFR1, TR, Trfr, p90, T9, TRFR
Reactivity
Human
(195), (110), (19), (11), (1), (1), (1)
Host
Mouse
(153), (86), (53), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(40), (33), (29), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(209), (74), (59), (57), (34), (24), (16), (13), (11), (10), (5), (4), (4), (3), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN264291
253.00 $
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Clone BGX-24
Isotype IgG1
Characteristics Synonyms: TfR1, p90, Transferrin receptor protein 1
Purification Purified
Alternative Name CD71 / TFRC
Background CD71 antigen expression is low on normal resting lymphocytes and is expressed on all cells upon activation. The transferrin receptor is essential for iron transport into proliferating cells, such as mitogen-activated and alloantigen-activated lymphoblasts. The transferrin receptor is also present on early erythroid cells but is lost as reticulocytes differentiate into mature erythrocytes.Synonyms: TfR1, Transferrin receptor protein 1, p90
UniProt P02786
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry. Study of discrimination of activated lymphocytes from resting lymphocytes. Study of erythropoiesis. Analysis of metabolic activation or cellular proliferation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Protocol PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze.
Restrictions For Research Use only
Buffer PBS containing 0.08 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Loken, Shah, Dattilio et al.: "Flow cytometric analysis of human bone marrow: I. Normal erythroid development." in: Blood, Vol. 69, Issue 1, pp. 255-63, 1987 (PubMed).

Jefferies, Brandon, Hunt et al.: "Transferrin receptor on endothelium of brain capillaries." in: Nature, Vol. 312, Issue 5990, pp. 162-3, 1984 (PubMed).

Phillips, Le, Lanier: "Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens." in: The Journal of experimental medicine, Vol. 159, Issue 4, pp. 993-1008, 1984 (PubMed).

Judd, Poodry, Strominger: "Novel surface antigen expressed on dividing cells but absent from nondividing cells." in: The Journal of experimental medicine, Vol. 152, Issue 5, pp. 1430-5, 1981 (PubMed).

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