BCL2-Like 1 (BCL2L1) (AA 3-14) antibody

Details for Product No. ABIN264325
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Antigen
Epitope
AA 3-14
(33), (32), (22), (21), (12), (10), (8), (7), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(316), (183), (157), (43), (43), (42), (12), (6), (4), (3), (1), (1)
Host
Mouse
(249), (94), (3), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(14), (8), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1)
Application
Western Blotting (WB)
(237), (111), (99), (76), (58), (42), (42), (40), (22), (16), (15), (4), (3), (2), (2), (1)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN264325
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Immunogen Synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence.
Clone 2H12
Isotype IgG2a
Characteristics Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
Purification Protein A/G Chromatography.
Alternative Name Bcl-2-Like 1
Background Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. Theratio of bcl-xl to other family members is believed to modulate the apoptotic process.
UniProt Q07817
Research Area Cancer
Application Notes Suitable for use in Western Blot: 1-5 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS with no preservative or carrier protein added.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Expiry Date 12 months
Supplier Images
anti-BCL2-Like 1 (BCL2L1) (AA 3-14) antibody anti-BCL2-Like 1 (BCL2L1) (AA 3-14) antibody
Background publications Boise, González-García, Postema et al.: "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death." in: Cell, Vol. 74, Issue 4, pp. 597-608, 1993 (PubMed).

Hsu, Wolter, Youle: "Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3668-72, 1997 (PubMed).

Hsu, Youle: "Nonionic detergents induce dimerization among members of the Bcl-2 family." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13829-34, 1997 (PubMed).

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