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Details for Product No. ABIN264325

Bcl-2-Like 1 (AA 3-14) antibody

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»Alternatives AA 3-14
»Alternatives Human, Mouse (Murine), Rat (Rattus)
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN264325
Quantity 0.1 mg
313.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence.
Clone 2H12
Isotype IgG2a
Characteristics Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
Purification Protein A/G Chromatography.
Background Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. Theratio of bcl-xl to other family members is believed to modulate the apoptotic process.
UniProt Q07817
Research Area Cancer
Application Notes Suitable for use in Western Blot: 1-5 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS with no preservative or carrier protein added.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Boise, González-García, Postema et al.: "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death." in: Cell, Vol. 74, Issue 4, pp. 597-608, 1993 (PubMed).

Hsu, Wolter, Youle: "Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3668-72, 1997 (PubMed).

Hsu, Youle: "Nonionic detergents induce dimerization among members of the Bcl-2 family." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13829-34, 1997 (PubMed).

Alternatives for antigen "Bcl-2-Like 1", type "Antibodies"
Hosts (28), (10), (1)
Reactivities (39), (30), (23), (3), (2), (1)
Applications (31), (26), (6), (6), (6), (4), (2), (2), (2)
Conjugates (1), (1), (1)
Epitopes (6), (4), (3), (1), (1), (1), (1), (1), (1)