Cyclin D2 antibody (CCND2)

Details for Product anti-CCND2 Antibody No. ABIN264332, Supplier: Log in to see
Antigen
  • si:ch211-240j22.2
  • ccnd2
  • CCND2
  • kiak0002
  • zgc:162280
  • LOC100224096
  • KIAK0002
  • BF642806
  • C86853
  • Vin-1
  • Vin1
  • cD2
  • 2600016F06Rik
  • AI256817
  • cyclin D2, b
  • cyclin D2
  • G1/S-specific cyclin-D2
  • cyclin D2, a
  • cyclin D1
  • ccnd2b
  • ccnd2-b
  • CCND2
  • ccnd2
  • ccnd2a
  • LOC100224096
  • CCND1
  • Ccnd2
  • ccnd2-a
Alternatives
anti-Rat (Rattus) Cyclin D2 antibody for Blocking Reagent
Reactivity
Human, Mouse (Murine), Rat (Rattus)
177
90
62
2
1
1
1
1
1
1
1
1
Host
Mouse
124
65
Clonality (Clone)
Monoclonal ()
Conjugate
This Cyclin D2 antibody is un-conjugated
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
153
52
33
31
29
19
15
13
13
12
6
4
3
3
2
1
1
1
1
Options
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Immunogen His-tagged recombinant full length Cyclin D2 protein recognizing a 34 kD protein.
Clone DCS-3-1
Isotype IgG2a
Specificity This antibody recognizes a 34 kDa protein.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse and Rat.
Characteristics Synonyms: Cyclin-D2, CCND2
Purification Affinity chromatography on Protein A/G
Alternative Name Cyclin D2 (CCND2 Antibody Abstract)
Background Cyclin D2 is a G1 cyclin required for a G1 phase progression. Like Cyclin D1, it is activated by the same mechanisms. It is well suited for neutralization of Cyclin D2 activity in vivo.Synonyms: CCND2, Cyclin-D2
Molecular Weight 33 kDa
Gene ID 894
UniProt P30279
Research Area Cancer, Cell Cycle
Pathways Cell Division Cycle, Mitotic G1-G1/S Phases
Application Notes Western Blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, 0.08 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Lukas, Bartkova, Welcker, Petersen, Peters, Strauss, Bartek: "Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types." in: Oncogene, Vol. 10, Issue 11, pp. 2125-34, 1995 (PubMed).

Bartkova, Lukas, Müller, Strauss, Gusterson, Bartek: "Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer." in: Cancer research, Vol. 55, Issue 4, pp. 949-56, 1995 (PubMed).