PTGER2 antibody

Catalog No. ABIN264447

Product Details anti-PTGER2 Antibody

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Reactivity: Human, Rat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTGER2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects Prostaglandin E2 Receptor EP2 subtype.

Characteristics: Synonyms: Prostaglandin E receptor 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2, PGEreceptor EP2, PGE2 receptor EP2 subtype, EP2

Purification: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman EP2 receptor protein and mouse myeloma cells.

Clone: 3-00E-006

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1-5 μg/mL. Positive Control: Porcine brain lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.08 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for PTGER2

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Alternative Name: PTGER2 (PTGER2 Products)

Synonyms: EP2 antibody, Ptgerep2 antibody, ptger2 antibody, ptger2l antibody, zgc:63974 antibody, MGC69060 antibody, PTGER2 antibody, Ptger-ep2 antibody, si:ch211-13n20.1 antibody, si:dkey-29m11.3 antibody, zgc:136608 antibody, prostaglandin E receptor 2 antibody, prostaglandin E receptor 2 (subtype EP2) antibody, prostaglandin E receptor 2a (subtype EP2) antibody, prostaglandin E receptor 2 S homeolog antibody, prostaglandin E receptor 2b (subtype EP2) antibody, PTGER2 antibody, Ptger2 antibody, ptger2a antibody, ptger2.S antibody, ptger2b antibody

Background: Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. It's wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.Synonyms: EP2, PGE receptor EP2, PGE2 receptor EP2 subtype, Prostaglandin E receptor 2, Prostaglandin E2 receptor EP2, Prostanoid EP2 receptor

Gene ID: 5732

UniProt: P43116