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S1PR4 antibody (C-Term) (FITC)

S1PR4 Reactivity: Human WB, FACS Host: Mouse Monoclonal 1 FITC
Catalog No. ABIN264452
  • Target See all S1PR4 Antibodies
    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
    Binding Specificity
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 40
    • 32
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 51
    • 4
    Mouse
    Clonality
    • 53
    • 2
    Monoclonal
    Conjugate
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S1PR4 antibody is conjugated to FITC
    Application
    • 41
    • 18
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Specificity
    Recognizes EDG-6/S1P4 (C-term).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Characteristics
    Synonyms: S1P receptor 4, S1PR4, EDG6, LPC1, SLP4, Sphingosine 1-phosphate receptor 4, Endothelialdifferentiation G-protein coupled receptor 6
    Immunogen
    Hybridoma produced by the fusion of splenocytes from mice immunized with Uniquesynthetic peptide derived from the C-terminal of the EDG6 (S1P4) protein and mousemyeloma cells.
    Clone
    1
    Isotype
    IgG1
    Top Product
    Discover our top product S1PR4 Primary Antibody
  • Application Notes
    Western Blot. Flow Cytometry: Use 1 μg/10^6 cells. NOTE: Epitope for the antibody is the C-terminal of the EDG6 protein. The C-terminal is anintracellular region and cells need to be permeablized prior to staining with antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as a preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
    Shelf life: One year from despatch.
    Expiry Date
    12 months
  • Target
    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
    Alternative Name
    S1PR4 / EDG6 (S1PR4 Products)
    Synonyms
    EDG6 antibody, edg6 antibody, LPC1 antibody, S1P4 antibody, SLP4 antibody, Edg6 antibody, Lpc1 antibody, S1p4 antibody, sphingosine-1-phosphate receptor 4 antibody, sphingosine-1-phosphate receptor 4 S homeolog antibody, S1PR4 antibody, s1pr4.S antibody, S1pr4 antibody
    Background
    EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6
    Gene ID
    8698
    UniProt
    O95977
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