HIRA antibody (N-Term)

Catalog No. ABIN264454

Product Details anti-HIRA Antibody

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Binding Specificity: AA 1-200, N-Term

Reactivity: Saccharomyces cerevisiae

Host: Mouse

Clonality: Monoclonal

Conjugate: This HIRA antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Synonyms: DGCR1, HIR, TUP1-like enhancer of split protein 1, HIR histone cell cycle regulation defectivehomolog A

Purification: Purified

Immunogen: Recombinant protein derived from the amino acids 1-200 of yeastt TUP1 protein

Clone: 1E1

Isotype: IgG

Application Details

Application Notes: Western blot (5-10 μg/mL). Positive Control: Mav108 cells expressing recombinant TUP1 protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing containing 0.08 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Alternative Name: HIRA / TUPLE1 (HIRA Products)

Synonyms: HIRA antibody, wu:fb97b07 antibody, wu:fi43b08 antibody, si:ch211-188g24.3 antibody, AA138857 antibody, D16Ertd95e antibody, N28177 antibody, Tuple1 antibody, DGCR1 antibody, TUP1 antibody, TUPLE1 antibody, dgcr1 antibody, hira-A antibody, tup1 antibody, tuple1 antibody, homolog of histone chaperone HIRA antibody, histone cell cycle regulator antibody, histone cell cycle regulator a antibody, protein HIRA antibody, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antibody, HIRA antibody, histone cell cycle regulator S homeolog antibody, histone chaperone HIRA-like protein antibody, Tuple1/HirA antibody, HIRA antibody, hira antibody, LOC100052845 antibody, LOC100352472 antibody, LOC100407742 antibody, LOC100450459 antibody, LOC100467668 antibody, LOC100581135 antibody, LOC486424 antibody, Hira antibody, LOC732736 antibody, hira.S antibody

Background: Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.Synonyms: DGCR1, HIR, HIR histone cell cycle regulation defective homolog A, TUP1-like enhancer of split protein 1

Gene ID: 7290

UniProt: P54198

Pathways: Chromatin Binding