Did you know that you can buy products from over 140 different suppliers from us?

serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) antibody

Details for Product No. ABIN264518
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms SERPINB9, BB283241, CAP-3, CAP3, PI-9, PI9, Spi6, ovalbumin
Reactivity
Human
(50), (10), (10)
Host
Mouse
(24), (20), (5), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Flow Cytometry (FACS)
(46), (23), (15), (10), (8), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN264518
500.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantPI-9 produced in P. pastoris and mouse myeloma cells.
Clone 7D8
Isotype IgG1
Characteristics Synonyms: PI9, Serpin B9, Cytoplasmic antiproteinase 3, CAP-3, CAP3, Proteinase inhibitor 9
Purification Purified
Alternative Name SERPINB9
Background This antibody detects the human intracellular serpin, PI 9, which is present in cytotoxicand dendritic cells to protect against the proapoptotic protease, granzyme B. Pi 9 may beunregulated by tumours to evade the immune system.
UniProt P50453
Research Area Proteases
Application Notes Flow cytometry. Immunohistochemistry (frozen & paraffin*). Western Blot. Positive Control: Found in the cytoplasm. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline with 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Hirst, Buzza, Sutton et al.: "Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction." in: Molecular human reproduction, Vol. 7, Issue 12, pp. 1133-42, 2001 (PubMed).

Hirst, Buzza, Bird et al.: "The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 805-15, 2003 (PubMed).

Validation Images
back to top