anti-CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (C-Term)

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Antigen
Alternatives
Epitope
C-Term
(56), (39), (27), (25), (19), (6), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(274), (145), (139), (6), (4), (4), (3), (1), (1), (1)
Host
Rabbit
(223), (36), (19), (1)
Clonality
Polyclonal
Conjugate
This CBL antibody is un-conjugated
(7), (7), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Application
Western Blotting (WB)
(196), (84), (80), (65), (56), (39), (24), (16), (9), (5), (4), (4), (3), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
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Immunogen Synthetic peptide corresponding to 14 amino acids near the carboxy terminal of human cbl
Specificity This antibody reacts with the carboxy terminus of human, mouse and rat c-Cbl. The mammalian cbl family of ubiquitin ligases consists of three homologs known as c-Cbl, Cbl-B and Cbl-3. Of the three known homologs in the cbl family this antibody reacts specifically with c-Cbl. Multiple isoforms of c-Cbl have been reported.
Purification Immunoaffinity chromatography
Alternative Name CBL / RNF55 (CBL Antibody Abstract)
Background Synonyms: CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, Proto-oncogene c-CBL, RING finger protein 55, Signal transduction protein CBL, c-CBL
Gene ID 867
NCBI Accession NP_005179
UniProt P22681
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway
Application Notes Western blot: 0.5 - 1,0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Weissman: "Themes and variations on ubiquitylation." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 3, pp. 169-78, 2001 (PubMed).

Catalog No. ABIN264539
$544.50
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