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Peptidyl-tRNA Hydrolase 2 (PTRH2) antibody

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Human, Mouse (Murine)
(88), (25), (18), (1), (1), (1), (1)
(84), (2), (2)
(5), (5), (5), (5), (5), (5), (1)
Western Blotting (WB)
(84), (47), (33), (9), (8), (6), (3), (2), (2)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Synthetic peptide corresponding to 16 amino acids near the center of human Bit1
Specificity This antibody reacts to Bcl-2 Inhibitor of Transcription 1 (Bit1).
Purification Immunoaffinity chromatography
Alternative Name PTRH2 / BIT1 (PTRH2 Antibody Abstract)
Background PTRH2 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin like enhancer of split (TLE) protein and induces caspase independent apoptosis.Synonyms: CGI-147, PTH2, Peptidyl-tRNA hydrolase 2 mitochondrial
Gene ID 51651
NCBI Accession NP_057161
UniProt Q9Y3E5
Application Notes Western Blot: 1 - 2g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).

Catalog No. ABIN264603

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