Peptidyl-tRNA Hydrolase 2 (PTRH2) antibody

Details for Product No. ABIN264603
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Antigen
Synonyms BIT1, PTH2, Bit1, CGI-147, A230072I16Rik, RGD1306819, wu:fj09f02, zgc:109954
Reactivity
Human, Mouse (Murine)
(47), (32), (24), (12), (12), (12), (1)
Host
Rabbit
(47), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (19), (12), (10), (9), (8), (4), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN264603
Quantity 0.1 mg
Price
544.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide corresponding to 16 amino acids near the center of human Bit1
Specificity This antibody reacts to Bcl-2 Inhibitor of Transcription 1 (Bit1).
Purification Immunoaffinity chromatography
Alternative Name PTRH2 / BIT1
Background PTRH2 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin like enhancer of split (TLE) protein and induces caspase independent apoptosis.
Alternate names: CGI-147, PTH2, Peptidyl-tRNA hydrolase 2 mitochondrial
Gene ID 51651
NCBI Accession NP_057161.1
UniProt Q9Y3E5
Application Notes Western Blot: 1 - 2g/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% Sodium Azide
Preservative Sodium azide
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).

Hosts (47), (2)
Reactivities (47), (32), (24), (12), (12), (12), (1)
Applications (39), (19), (12), (10), (9), (8), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (7), (3), (2), (2), (2), (1)
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