Peptidyl-tRNA Hydrolase 2 (PTRH2) antibody

Details for Product No. ABIN264603
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Antigen
Synonyms BIT1, PTH2, A230072I16Rik, Bit1, CGI-147, wu:fj09f02, zgc:109954, RGD1306819
Reactivity
Human, Mouse (Murine)
(60), (31), (23), (12), (12), (12), (1)
Host
Rabbit
(58), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(50), (29), (18), (10), (9), (7), (3), (2)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN264603
544.50 $
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Immunogen Synthetic peptide corresponding to 16 amino acids near the center of human Bit1
Specificity This antibody reacts to Bcl-2 Inhibitor of Transcription 1 (Bit1).
Purification Immunoaffinity chromatography
Alternative Name PTRH2 / BIT1
Background PTRH2 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin like enhancer of split (TLE) protein and induces caspase independent apoptosis.
Alternate names: CGI-147, PTH2, Peptidyl-tRNA hydrolase 2 mitochondrial
Gene ID 51651
NCBI Accession NP_057161
UniProt Q9Y3E5
Application Notes Western Blot: 1 - 2g/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).

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