interleukin 23, alpha subunit p19 (IL23A) (C-Term) antibody

Details for Product No. ABIN264657
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Antigen
Synonyms IL-23, IL-23A, IL23P19, P19, SGRF, p19, IL23, il23p19, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1
Epitope
C-Term
(19), (15), (4), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(75), (47), (14), (1)
Host
Rabbit
(62), (17), (9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(61), (32), (16), (13), (10), (10), (10), (6), (4), (4), (4), (2), (2), (2), (2), (1)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN264657
544.50 $
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Immunogen Synthetic peptide corresponding to 16 amino acids near the carboxy terminus of human IL-23
Specificity This antibody reacts with the C-terminal of IL-23.
Purification Immunoaffinity chromatography
Alternative Name Interleukin-23 alpha / IL23A
Background IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes.
Alternate names: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID 51561
NCBI Accession NP_057668
UniProt Q9NPF7
Application Notes Western blot: 1 - 4g/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Oppmann, Lesley, Blom et al.: "Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12." in: Immunity, Vol. 13, Issue 5, pp. 715-25, 2001 (PubMed).

Sheibanie, Tadmori, Jing et al.: "Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 18, Issue 11, pp. 1318-20, 2004 (PubMed).

Hunter: "New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions." in: Nature reviews. Immunology, Vol. 5, Issue 7, pp. 521-31, 2005 (PubMed).

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