Did you know that you can buy products from over 140 different suppliers from us?

Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) antibody

Details for Product No. ABIN264770
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms APO3L, DR3LG, TWEAK, Apo3l, Dr3l, Dr3lg, Tweak
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(59), (34), (10), (2)
Host
Rabbit
(40), (16), (12), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (6)
Application
Western Blotting (WB)
(53), (28), (25), (16), (9), (7), (7), (4), (4), (2), (2), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN264770
544.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant Human TWEAK.
Specificity This antibody reacts to TWEAK.
Purification DEAE Chromatography
Alternative Name TWEAK / TNFSF12
Background TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. It is widely expressed, has high constitutive expression in heart placenta, lung, muscle, kidney, pancreas, and HUVEC. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis.
Alternate names: APO3 ligand, APO3L, DR3LG, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12
Gene ID 8742
NCBI Accession NP_003800.1
UniProt O43508
Application Notes Western blot: 0.5 - 1g/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Chicheportiche, Bourdon, Xu et al.: "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32401-10, 1998 (PubMed).

Wiley, Winkles: "TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor." in: Cytokine & growth factor reviews, Vol. 14, Issue 3-4, pp. 241-9, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN264770
544.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
Did you look for something else?
back to top