Add to Basket
Order hotline:
 |
+1 404 474 4654 |
 |
+1 888 205 9894 (TF) |
X-Box Binding Protein 1 (XBP1) (N-Term) antibody
| Antigen | X-Box Binding Protein 1 (XBP1) |
| Synonyms | XBP2, TREB5, XBP-1, TREB-5, D11Ertd39e, cb918, treb5, trebf, xbp1a, xbp1b, id:ibd1195, wu:fb02h05, wu:fb63f10, HTF, xbp1, MGC53678, MGC130816, xbp2, xXBP1, MGC76163, XBP1, XBPP1, MGC127699 |
| Epitope |
 Alternatives N-Term |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
|
| Catalog no. | ABIN264807 |
| Quantity | 0.5 mg (1.0 mg/ml) (Variants) |
| Price | 1,540.00 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: XBP-1, XBP2, X-box-binding protein 1, Tax-responsive element-binding protein 5 |
| Alternative name | XBP1 / TREB5 |
| Swiss-Prot | P17861 |
| Immunogen | Synthetic peptide corresponding to 18 amino acids near the amino terminus of humanXBP-1 |
| Cross-Reactivity | Human, Mouse (Murine) |
| Description | This gene encodes a transcription factor that regulates MHC class II genes by binding to apromoter element referred to as an X box. The protein contains two domains commonlyfound in transcription factors that confer DNA binding and dimerization capability. Thisgene product was also separately identified as a cellular transcription factor that binds toan enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increaseexpression of viral proteins by acting as the DNA binding partner of a viral transactivator. There is also a recent finding that the same agents that cause an ER stress response, theunfolded protein response, also increase transcription of this gene. This increase intranscription requires an ER stress response consensus binding element in the promoter. |
| Specificity | This antibody reacts with XBP-1. Recognizes the spliced and the non-spliced isoforms of XBP-1. Species: Human and Mouse. Others not tested. |
Application Details
| Application Notes | Western blot: 1-2 µg/ml. Immunocytochemistry. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 1.0 mg/ml |
| Purification | Aff - Purified |
| Buffer | PBS containing 0.02% Sodium Azide as preservative. |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "X-Box Binding Protein 1 (XBP1)", type "Antibodies"
| Hosts | Rabbit (9), Mouse (7), Goat (6) |
| Reactivities | Human (20), Mouse (Murine) (8), Rat (Rattus) (5), Dog (Canine) (4) |
| Applications | Western Blotting (WB) (21), Enzyme Immunoassay (EIA) (11), Immunofluorescence (IF) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), ELISA (Detection) (3), ELISA (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1) |
| Epitopes | AA 2-160 (2), N-Term (2), C-Term (1) |
