This antibody reacts to serine/threonine protein phosphatase 2A/B beta. Minimal cross reactivity against 2A/Bg .
Purification
Purified
Immunogen
Purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Gly-Glu-Glu- Asp-Ile-Asp-THr-Arg-Lys-Ile-Asn-Asn-Ser-Phe-COOH. This peptide antibody corresponds to N- terminal peptide of PP2A/Bb regulatory subunit having a MW of 53kDa. The sequence used is amino acid 2-14.
PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.Synonyms: B55-beta isoform, PP2A subunit B B-beta isoform, PR55-beta isoform, R2-beta isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta