PPP2R5D antibody (N-Term)

Catalog No. ABIN264943

Product Details anti-PPP2R5D Antibody

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5D antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to PP 2A/B delta.

Purification: Purified

Immunogen: Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta

Isotype: IgG

Application Details

Application Notes: Western Blotting. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Alternative Name: PPP2R5D (PPP2R5D Products)

Synonyms: B56D antibody, B'delta antibody, TEG-271 antibody, Tex271 antibody, zgc:73160 antibody, zgc:77529 antibody, ppp2r5d antibody, MDS026 antibody, protein phosphatase 2 regulatory subunit B'delta antibody, protein phosphatase 2, regulatory subunit B', delta antibody, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, PPP2R5D antibody, Ppp2r5d antibody, ppp2r5d antibody, LOC100176996 antibody, PPP2R2D antibody

Background: PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Ba, Bb and Bg . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. Bd is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.Synonyms: PP2A B subunit B'delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

Gene ID: 5528

NCBI Accession: NP_006236

UniProt: Q14738

Pathways: PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades