KCNA4
Reactivity: Human
IF (cc), IF (p)
Host: Rabbit
Polyclonal
Alexa Fluor 750
Application Notes
Western Blot: 1 - 10 μg/mL. Immunofluorescence. Immunoprecipitation. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Phosphate buffered saline with 0.08 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
Kv1.4 (KCNA4)
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential (1). Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies. The most distinctively characterized is that of the Kv1 shaker class (2). The rabbit anti kv 1.4 ptassium channel antibody recognizes a 90 kDa protein by western blot on rat hippocampal membranes and a protein of 76 kDa in lysates of HEK293 cells (3).Synonyms: HBK4, HPCN2, HUKII, Potassium voltage-gated channel subfamily A member 4, RCK4, RHK1, RK3, Voltage-gated potassium channel subunit Kv1.4