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CACNA1A antibody

CACNA1A Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265030
  • Target See all CACNA1A Antibodies
    CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))
    Reactivity
    • 19
    • 13
    • 1
    Rat
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA1A antibody is un-conjugated
    Application
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    Synthetic peptide derived from the rat alpha1A calcium channel conjugated to KLH.
    Isotype
    IgG
    Top Product
    Discover our top product CACNA1A Primary Antibody
  • Application Notes
    Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Target
    CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))
    Alternative Name
    CACNA1A (CACNA1A Products)
    Synonyms
    cav2.1 antibody, cacna-a antibody, ca(v)2.1 antibody, cacna1a antibody, si:ch211-237k17.1 antibody, BccA1 antibody, Cav2.1 antibody, rbA-1 antibody, APCA antibody, BI antibody, CACNL1A4 antibody, CAV2.1 antibody, EA2 antibody, FHM antibody, HPCA antibody, MHP antibody, MHP1 antibody, SCA6 antibody, Caca1a antibody, Cacnl1a4 antibody, Ccha1a antibody, alpha1A antibody, la antibody, leaner antibody, nmf352 antibody, rkr antibody, rocker antibody, tg antibody, tottering antibody, CACH4 antibody, CACN3 antibody, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog antibody, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a antibody, calcium voltage-gated channel subunit alpha1 A antibody, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit antibody, P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A antibody, cacna1a.S antibody, cacna1aa antibody, CACNA1A antibody, Cacna1a antibody, LOC395892 antibody
    Background
    Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1a gives rise to p and/or q-type calcium currents. P/q-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by the funnel toxin (ftx) and by the omega-agatoxin-IVA (omega-aga-IVA). They are however insensitive to dihydropyridines (dhp), and omega- conotoxin-GVIA (omega-ctx-GVIA). voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the poreforming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.Synonyms: Brain calcium channel I, CACH4, CACN3, CACNL1A4, Calcium channel L type alpha-1 polypeptide isoform 4, Cav2.1, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-gated calcium channel subunit alpha
    Gene ID
    10116
    UniProt
    P54282
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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