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CACNA1E antibody

CACNA1E Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265032
  • Target See all CACNA1E Antibodies
    CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
    Reactivity
    • 21
    • 4
    • 4
    • 1
    Human, Rat
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA1E antibody is un-conjugated
    Application
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    This antibody recognizes Alpha 1E Calcium Channel CACNA1E.
    Cross-Reactivity (Details)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.
    Purification
    Ammonium sulfate precipitation
    Immunogen
    Synthetic peptide derived from the Rat alpha1E Calcium Channel conjugated to KLH.
    Isotype
    IgG
    Top Product
    Discover our top product CACNA1E Primary Antibody
  • Application Notes
    Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.08 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Target
    CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
    Alternative Name
    CACNA1E (CACNA1E Products)
    Synonyms
    caV2.3 antibody, CACNA1E antibody, BII antibody, CACH6 antibody, CACNL1A6 antibody, Cav2.3 antibody, A430040I15 antibody, Cach6 antibody, Cacnl1a6 antibody, Cchra1 antibody, alpha1E antibody, CACHA1E antibody, calcium voltage-gated channel subunit alpha1 E antibody, calcium channel, voltage-dependent, R type, alpha 1E subunit antibody, CACNA1E antibody, cacna1e antibody, Cacna1e antibody
    Background
    Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by nickel, and partially by omega-agatoxin-iiia (omega-aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-ctx-GVIA), and omega-agatoxin-IVA (omega-aga-IVA). Calcium channels contaning alpha-1e subunit could be involved in the modulation of firing patterns of neurons.Synonyms: Brain calcium channel II, CACH6, CACNL1A6, Cav2.3, Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-gated calcium channel subunit alpha
    Gene ID
    777
    NCBI Accession
    NP_000712
    UniProt
    Q15878
    Pathways
    Carbohydrate Homeostasis
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