CACNA2D1 antibody

Catalog No. ABIN265035

Product Details anti-CACNA2D1 Antibody

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA2D1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: Synthetic peptide derived from the rat alpha2/delta calcium channel conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for CACNA2D1

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Alternative Name: CACNA2D1 (CACNA2D1 Products)

Synonyms: CACNA2D1 antibody, DKFZp469K2211 antibody, CACNA2 antibody, CACNL2A antibody, CCHL2A antibody, Ca(v)alpha2delta1 antibody, Cacna2 antibody, Cchl2a antibody, CCHLA2 antibody, DHSCCA antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antibody, calcium channel, voltage-dependent, alpha2/delta subunit 1 antibody, CACNA2D1 antibody, cacna2d1 antibody, Cacna2d1 antibody

Background: The calcium channel alpha2/delta subunit is a glycosylated structural subunit consisting of the alpha2 subunit and the delta peptide. There is distinctive alpha2 subunit expression in rat spinal cord and dorsal root ganglia (DRG) There are two forms of the alpha2 subunit in DRG that are different from the alpha2 subunit in other tissues examined, at least at the glycosylation level. Thus, post-translational modification may be important in tissue specific and functional expression of the alpha2/delta subunit (2). alpha2/delta and beta1b interact with alpha1G to increase trafficking of, or stabilize, functional alpha1G channels expressed at the plasma membrane.(3)Synonyms: CACNL2A, CCHL2A, MHS3, Voltage-dependent calcium channel subunit alpha-2/delta-1

Gene ID: 10116

UniProt: P54290